Award Data

This Small Business Technology Transfer Research (STTR) Phase II project will extend the basic science of linear interference delay effect filters, enabling ultra-wideband tunable RF filters for all types of RF receivers and instrumentation. It will also extend the engineering science of implementing such filters as integrated circuits. And, its distortion filtering aspect will enable enable signa ...

DESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...

DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

DESCRIPTION provided by applicant In there were new cases of head and neck cancers HNC in the United States Early detection of new and locally recurrent cancers is clinically important to reduce not only cancer related mortality but also treatment associated morbidity as it impacts multiple organ functions including respiration olfaction hearing eating swallowing and speak ...

DESCRIPTION provided by applicant The leading cause of mortality in patients with cystic fibrosis CF is pulmonary failure from lung infections and the predominant organism isolated from these infections is the bacterium Pseudomonas aeruginosa Lung infections of CF patients persist over the lifetime of the patients and are impossible to eradicate due to the ability of bacteria to form biofi ...

DESCRIPTION provided by applicant Heart attacks i e myocardial infarction or MI occur in more than million patients annually Advances in pharmacological therapy have dramatically improved survival following the initial MI Consequently the number of patients with previous MI continues to increase and as a result put in jeopardy millions of patients for development of heart failure I ...

This Small Business Technology Transfer Research (STTR) Phase II project has the overall objective of developing a multi-component melt spinning approach to produce a new family of high performance fibers using standard low-cost polymers. The new high-strength and/or high-modulus polymeric fiber is to be made using cutting-edge but commercially available spinning technology and an innovative and ...

This Small Business Technology Transfer (STTR) Phase II project seeks to identify new and improved promoters to create enhanced genetically modified crops. Plant biotechnology relies on the insertion of promoter-gene constructs into plants. The promoter is the portion of DNA that controls when and where a gene is expressed. The relatively few plant promoters in use today have significant limitatio ...

DESCRIPTION (provided by applicant): The current proposal responds to program announcement PA-09-081, which has extended and replaced our Phase I announcement PAS-06-131 Applications of Imaging and Sensor Technologies for Clinical Aging Research. The purpose of the announcement is to improve imaging methods for measuring age-related changes in regulation of complex physiologic systems, including ...