Award Data

The broader impact/commercial potential of this project is the rapid, cost-effective detection of natural gas leakage to improve public safety, mitigate global climate change, and decrease product loss. Natural gas is the largest provider of power in the United States. However, more than 80 Tg of leakage occurs at well pads and pipelines during production alone. Such leakage poses a public health ...

The broader impact/commercial potential of this project will enable Unmanned Aerial Systems (UAS or drones) to safely and reliably operate from moving vehicles and moving vessels at sea. There is an immediate need for this capability in many industries. In commercial fishing, drones will replace manned aircraft for fish-finding operations, radically reducing cost and risk. In maritime security, dr ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project will be to develop a new tool to safely and nondestructively deliver genes and other materials into large numbers cells at the same time. New forms of therapies for cancer and other intractable diseases take advantage of a patient's own cells, re-engineered in the laboratory to target a tumor ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project is the reduction of significant disease flare-ups in patients with Chronic Obstructive Pulmonary Disease (COPD), increase in patient quality-of-life, and a reduction of expensive and unnecessary healthcare utilization. Current at-home care support for COPD patients is often completely missing or consi ...

The broader impact / commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to enable electrification of remote oil & gas processes to reduce methane emissions, improve on-site safety, and provide leak-detection and monitoring capabilities. This will be achieved by developing a robust, efficient, small-scale power generator capable of converting on-site fuel to e ...

In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

GeneCapture, Inc. is proposing to develop a rapid in vitro diagnostic prototype using our patented molecular-based CAPTURE (ConfirmActive Pathogens Through Unamplified RNA Expression) assay. Based on the results and experience gained in our Phase I STTR contractHDTRA1-16C-0061: Infectious Disease Diagnostics and Differentiation of Viral vs. Bacterial Infections for Point of Care Applications, we p ...

For effective protection against radiated threats, it is important to understand not only the physics of the threats, but also to quantify the effects they have on mission-critical electrical systems. Radiated vulnerability and susceptibility testing requires delivery of high peak power and peak electric fields to distant targets. The most practical solution to simulate such environments on large ...