Award Data

This STTR Phase I project will undertake the development of iron coordination complexes as alternatives for gadolinium contrast agents which are currently used in clinical MRI diagnostic exams. New MRI contrast agents are needed to serve the segment of the population who cannot tolerate Gd(III) agents. This includes patients with kidney disease and those who have frequent MRI scans and may accumul ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) will be to develop a platform to accelerate the engineering of biological products, including enzymes and pathways, for production of chemicals, additives, and therapeutics. Enzymes are used in household materials (detergents and cleaners) and in chemical processes (cheese production, and bioremediation of wa ...

Traumatic brain injury (TBI) often occurs when a sudden trauma or head injury disrupts the function of the brain. Common causes of TBI include damage caused by explosive devices, falls and vehicle or motorcycle accidents. Sepsis is the result of a massive immune response to bacterial infection that gets into the blood. Sepsis often leads to organ failure or injury, and has always been a significan ...

Micro-RDC has developed portable radiation effects test structures that scale to new process nodes.These structures will enable the investigation of the effects of radiation on the new technology from the material processing level as well as the circuit level.Fabricating the chosen structures and the refinement of software to extract the model parameters will be completed in this effort.A suite of ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project is a patient-centric engagement process that offers the best chance for enabling a scalable approach towards achieving the triple aim of improving care quality and outcomes, controlling health care costs and utilization, and increasing patient satisfaction. Currently the national healthcare c ...

The broader impact/commercial potential of this STTR Phase I project is a sustainable fruit and vegetable processing technology utilizing a new, low temperature technique that can extend the shelf life of pre-cut fruits and vegetables by months without using preservatives, chemicals, freezing, or refrigeration. The technology would enable: all-natural, shelf stable fruit and vegetable products tha ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project is the advancement of improved lithium ion batteries. The project will evaluate new battery chemistry enabling more rapid charging rates then currently available in the worldwide energy storage marketplace. Such high power density batteries would cater to a major emerging battery segment where current ...

The broader impact/commercial potential of this project covers a myriad of domains including wireless health-care, remote education, supply-chain management, public safety, anti-poverty initiatives, market-places, and entertainment. However, a more immediate work product from this effort is a powerful fully-digital mmWave software defined radio (SDR) platform that will be made available to academi ...

There is an urgent need to bypass or cross the blood brain barrier (BBB) to deliver drugs for TBI treatment. This project aims to develop targted intranasally delivered, magnetically propulsed, and targted nanoparticles for traumatic brain injury (TBI). In Phase I, we will demonstrate the design, fabrication, and in vitro characterization of proposed drug laden magnetic nanoparticles as well as co ...

Biological tissues collection is problematic and risky even under ideal conditions; when collection occurs in remote locations, or by minimally- trained personnel, as may occur in response to an emerging disease threat, risks are magnified. This proposal addresses this issue by developing a Field Fixation Unit (FFU) for specimen collection that utilizes single-use capsules pre-loaded with fixative ...