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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Flexible Microfluidic Process Technology for Biopharmaceutical Purification of Bacteriophages

    SBC: CFD RESEARCH CORPORATION            Topic: DHA21C002

    Multidrug resistant (MDR) bacterial wound infections remain a persistent challenge for front-line military medical providers in prolonged care treatment. Bacteriophage (phage) therapeutics have demonstrated preclinical and clinical efficacy against ESKAPEE infections. Phage production however remains a challenge to remove common pyrogen contaminants from phage products, including endotoxins (lipop ...

    STTR Phase II 2023 Department of DefenseDefense Health Agency
  2. Portable Phage Preparation Technology for Field Application

    SBC: CFD RESEARCH CORPORATION            Topic: A20BT023

    Bacteriophages (phages) are becoming important therapeutic candidates against multidrug resistant (MDR) bacterial infections. There is a need to isolate and concentrate phages collected from the field to enhance specimen storage stability for long-distance transport to specialized laboratories for subsequent analysis. Environmental phage preparation requires expensive, bulky instrumentation and in ...

    STTR Phase II 2023 Department of DefenseDefense Health Agency
  3. Synthetic Aperture Radar(SAR) Image Generation Data Augmentation

    SBC: ETEGENT TECHNOLOGIES, LTD.            Topic: DTRA21B001

    Machine learning algorithms have demonstrated performance on par with or superior to human analysts on large datasets when sufficient training data is available.  For military applications obtaining sufficient, truthed data is always a challenge.  Three approaches have been used for measured data collections to support sensor exploitation programs: coordinated collections, turntable measurements ...

    STTR Phase II 2023 Department of DefenseDefense Threat Reduction Agency
  4. Cervical Spine Health Improvement Products

    SBC: SWITCHBOX INC            Topic: DHA18B001

    Neck pain isacommon and disabling health impairmentaffecting both militaryand civilian populations. Dueto alack of objective,reliable,and actionablemetrics, occupational interventionsand treatment plansaretypically based on atrial-and error process that results in suboptimal outcomesand inflated costs. To address this problem, our objective will beto (1) develop an evidence-based technology that l ...

    STTR Phase II 2022 Department of DefenseDefense Health Agency
  5. Develop and demonstrate a technology for isolation of bacteriophages with enhanced antibiofilm activity

    SBC: CFD RESEARCH CORPORATION            Topic: DHA20B003

    The twenty-first century has seen a global rise in bacterial infections exhibiting antimicrobial-resistance (AMR). More than ninety percent of chronic wounds contain microbial biofilms that exhibit AMR, and the bacteria responsible for several of these recalcitrant infections are called ESKAPEE pathogens. Eradicating ESKAPEE pathogenic infections is challenging, but bacteriophage (phage) therapy i ...

    STTR Phase II 2022 Department of DefenseDefense Health Agency
  6. Flexible Microfluidic Process Technology for Biopharmaceutical Purification of Bacteriophages

    SBC: CFD RESEARCH CORPORATION            Topic: DHA21C002

    Multidrug resistant (MDR) bacterial wound infections remain a persistent challenge for front-line military medical providers in prolonged care treatment. Phage therapeutics have demonstrated preclinical and clinical efficacy against ESKAPEE infections. Phage production however remains a challenge to remove bacterial remnants including LPS endotoxins and other pyrogens. To meet regulatory requireme ...

    STTR Phase I 2022 Department of DefenseDefense Health Agency
  7. Phase II: In-field analysis of trace U and Pu by electrochemical pre-concentration

    SBC: AWAREABILITY TECHNOLOGIES, LLC            Topic: DTRA20B003

    The Defense Threat Reduction Agency (DTRA) needs a capability to collect and provide immediate presumptive analysis of radiological/nuclear samples of concern at the source of collection. Such in-field technologies should be capable of detecting and identifying trace quantities of elements and/or chemicals containing plutonium (Pu) and uranium (U), with a focus on chemicals specific to the nuclear ...

    STTR Phase II 2022 Department of DefenseDefense Threat Reduction Agency
  8. Obscured Object Training with GAN Augmented Synthetic Data

    SBC: ETEGENT TECHNOLOGIES, LTD.            Topic: DTRA21B001

    Machine learning algorithms have demonstrated performance on par with or superior to human analysts on large datasets when sufficient training data is available. For many military applications, sufficient truthed data over relevant operating conditions does not exist and is prohibitively expensive to obtain. A potential solution to thislack of measured datais synthetic data derived from physics si ...

    STTR Phase I 2022 Department of DefenseDefense Threat Reduction Agency
  9. Developing a Just-in-Time Refresher Trainer for Advanced Life Support in Austere Regions: Phase II

    SBC: UNVEIL LLC            Topic: DHA20B001

    Early recognition of impending decompensation and appropriate intervention is critical to patient survival. However, military personnel receive limited real-world practice in recognizing and treating impending decompensation in non-military patient populations. Tier 4 medics complete training in Advanced Cardiac Life Support (ACLS) and Pediatric Advanced Life Support (PALS), yet the skills learned ...

    STTR Phase II 2022 Department of DefenseDefense Health Agency
  10. Oxygen Production on Demand for Military Medical Needs

    SBC: GLOBAL RESEARCH & DEVELOPMENT INC            Topic: DHA17B005

    Topic 17B-005 calls for a new process for supplying medical grade O2 without the use of O2 bottles or pressure (or vacuum) swing absorption (PSA) technology. This is significant to the military for several reasons, because these two sources currently interfere with logistical supply of O2 to where it is required, namely field hospital units. PSA units reportedly have limited shelf life and supply ...

    STTR Phase II 2021 Department of DefenseDefense Health Agency
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