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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. End-System Performance-Adaptive Peak Link Utilization Transport Over Dedicated Lambda Grids

    SBC: Acadia Optronics, Llc            Topic: 41a

    Next generation network applications will require high, dynamically-stable transport throughputs at the application level, in order to support such tasks as computational monitoring and steering on supercomputers, massive wide-area data transfers between storage systems, and remote instrument control. However, the current shared IP infrastructure is unsuited for providing the unimpeded stable ban ...

    STTR Phase I 2008 Department of Energy
  2. OVARIAN CANCER PROTEOME VIA TISSUE MICRODISSECTION AND GEMINI TECHNOLOGIES

    SBC: CALIBRANT BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Biologically and clinically relevant proteomics data can only be generated if organ or tissue samples investigated consist of homogeneous cell populations, in which no unwanted cells of different types and/or developmen t stages obscure the results. Thus, several tissue microdissection technologies have been developed to provide a rapid and straightforward meth ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  3. Development of a low-cost hardware accelerator for 3D image registration.

    SBC: IGI TECHNOLOGIES, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Our overall goal is to develop a novel computing solution for automatic and accurate registration (spatial alignment) of three-dimensional (3D) medical images of any modality and any anatomy (rigid or deformable) in 1 m inute. Such capability currently does not exist. Existing image registration solutions have limited accuracy and/or limited applicability, prev ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  4. Multiplex Electroluminescent Assay for Detection of Hepatocellular Carcinoma

    SBC: MESO SCALE DIAGNOSTICS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of the proposed work is development of sensitive diagnostic serological assay panels for detection of hepatocellular carcinoma (HCC). Currently, the only biomarker used in HCC diagnosis is the measurement of al pha feto protein (AFP) in patient serum, which exhibits poor sensitivity and specificity. There is a need for alternative biomarkers to more ef ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  5. The Spiral Particle Detector for High Flux Neutron Beams

    SBC: PARTTEC, LTD.            Topic: 01a

    The Department of Energy¿s large research facilities need improved neutron detectors for thermal neutron instrumentation. Where large detector arrays are needed, single-wire overpressured 3He tube detectors are the detector of choice, because they are so cost effective. Though useful, current detectors do not meet the demands of current high intensity neutron sources, such as the Spallation N ...

    STTR Phase I 2008 Department of Energy
  6. Non-Invasive Optical Determination of GFR

    SBC: PHARMACOPHOTONICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): PharmacoPhotonics, LLC proposes research leading to a novel 2-photon in vivo fluorescence method for monitoring glomerular filtration rate (GFR) in acute kidney injury (AKI). AKI remains a vexing clinical problem result ing in unacceptably high patient mortality, development of chronic kidney disease and enhanced progression to end stage renal disease. Although ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  7. Accurate Protein Identification using Peptide Separation Information and Tandem M

    SBC: PREDICTIVE PHYSIOLOGY AND MEDICINE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): A significant problem currently hindering proteomics studies is the identification of peptides and proteins from mass spectral data. This problem is manifest in the difficulty to establish confidence limits of protein a nd peptide identifications. A serious concern is the tendency for the occurrence of false positive assignments. The development of an integrate ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  8. Substance Abuse Diagnostic Clinical Interview Simulation

    SBC: SIMMERSION LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Traditional methods for training clinicians and students in mental health disciplines in substance abuse assessment have been restricted to role-playing, mock interviews, textbook lessons, and video instruction. All of these tools have limitations for imparting real world experiences. Specifically, traditional methods of instruction do not include realistic in ...

    STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health
  9. Development of VPL Vaccine for RSV

    SBC: SIGMOVIR BIOSYSTEMS, INC.            Topic: NIAID

    Project Summary Human respiratory syncytial virus (RSV) is recognized as the single most important viral cause of acute respiratory disease in infants and young children worldwide. Elderly populations and immunocompromised individuals are also at significant risk for serious RSV disease. Despite this very substantial disease burden imposed by RSV worldwide, there are no vaccines available. Severa ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Non-ATP competitive inhibitors of cyclin dependent kinases as cancer therapeutics

    SBC: PPI PHARMACEUTICALS, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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