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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Non-ATP competitive inhibitors of cyclin dependent kinases as cancer therapeutics

    SBC: PPI PHARMACEUTICALS, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Hand Rehabilitation using Variable Assistance through Force and EMG Feedback

    SBC: Koronis Biomedical Technologies Corp.            Topic: NIA

    DESCRIPTION (provided by applicant): This project proposes to develop and evaluate a hand rehabilitation system for chronic hemiparetic stroke survivors that have lost their ability to full control their hand. Stroke is the leading cause of adult disability, and is the third leading cause of death in the United States. Stroke survivors often face a significant loss of functional motor control in ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A Millimeter-wave Tunable Cavity for Ultra-sensitive Solids and Liquids DNP-NMR at Low Budget

    SBC: DOTY SCIENTIFIC, INC.            Topic: NIA

    ? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Prevention of erectile dysfunction following prostate cancer radiotherapy

    SBC: Humanetics Corporation            Topic: NCI

    DESCRIPTION (provided by applicant): The aim of this proposal is to evaluate BIO 300 as an effective therapy to prevent and/or mitigate the erectile dysfunction (ED) that is commonly observed following radiotherapy (RT) for prostate cancer. Prostate cancer is the most common cancer among men in the United States. Approximately half of prostate cancer patients will undergo RT as a part of thei ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Multi-Blot Western Device

    SBC: YC BIOELECTRIC LLC            Topic: NIGMS

    DESCRIPTION (provided by applicant): The long-term objective of this STTR project is to commercialize the protein multi-blot Western device, which contributes to improving the productivity and accuracy of conventional Western blot analysis. Although Western blotting has been used for more than three decades, this labor-and-cost demanding technique remains a key routine for a majority of life scien ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. The Emotion Builder: An Intervention for Emotional Deficits after Brain Injury

    SBC: EMOTED, INC.            Topic: NICHD

    DESCRIPTION (provided by applicant): People with traumatic brain injury (TBI) are often plagued with socio-emotional deficits that include difficulty identifying emotions in oneself (alexithymia), difficulty recognizing other peoples' emotions (impaired affect recognition), and empathy loss. These highly prevalent deficits, ranging between 39-70% of the moderate to severe TBI population, are ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Sympathetic Nerve Activity Recorded From the Skin and Cardiac Arrhythmias

    SBC: ARRHYTHMOTECH            Topic: NHLBI

    DESCRIPTION (provided by applicant): The broad and long-term objective of this research project is to use, develop and market an instrument for the simultaneous recording of sympathetic nerve activity (SNA) and electrocardiogram (ECG) using electrodes on the skin. This method (neuECG) was discovered in Dr. Chen's research laboratory at the Krannert Institute of Cardiology, and a patent applic ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Location Initiated Individualized Texts for African American Adolescent Health

    SBC: MEI Research, Ltd            Topic: NIMHD

    DESCRIPTION (provided by applicant): Obesity in the U.S. has disproportionately affected African American (AA) adolescents who have almost twice the prevalence of obesity than their Caucasian peers. This is due in part to greater exposure to, and higher consumption of, 'fast' and calorie dense foods among minority vs. majority populations. Finding effective ways to address dietary habits ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Metal ion-functionalized soluble nanopolymers: A new analytical platform for plas

    SBC: Tymora Analytical Operations, LLC            Topic: 300

    DESCRIPTION provided by applicant Mass spectrometry based proteomics is an emerging technology that has seen possible applications everywhere The technique can potentially use one drop of our blood to reveal onset and progress of diseases Current Randamp D using plasma serum proteome sample sets however is severely limited by the high complexity and dynamic range of protein concentrations ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. A Rapid assay for RNA targeted drugs: Instrumentation Supplement

    SBC: NUBAD, LLC            Topic: 300

    DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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