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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Autism Treatment The Pivotal Skills Trainer

    SBC: ACCELERATIONS EDUCATIONAL SOFTWARE            Topic: N/A

    DESCRIPTION (provided by applicant): This STTR (Phase 1) project begins the translation of untapped scientific findings into an improved software tool for teaching children with autism spectrum disorders and other disabilities. The project evaluates a package to train teachers to use software called the Pivotal Skills Trainer and examines whether doing so improves preschoolers' functional communic ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Autism Education and Treatment with PowerPoint Software

    SBC: ACCELERATIONS EDUCATIONAL SOFTWARE            Topic: N/A

    DESCRIPTION (provided by applicant): PowerPoint(R) multimedia software is ubiquitous in our schools but its capacity for teaching children with autism spectrum and related disorders barely has been realized. This STTR (Phase I) project will begin to change this state of affairs by researching and developing empirically derived multimedia teaching tools. Encouraged by early-stage feasibility work, ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Pretest Probability Assessment for Pulmonary Embolism

    SBC: BREATHQUANT MEDICAL SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Pretest probability assessment (PTP) plays a pivotal role in the evaluation of pulmonary embolism (PE) in the emergency department (ED) and accurate PTP assessment can modify defensive test-ordering behavior by physicians. However, current methods of PTP assessment produce broad categories of risk that tend to over fit individual patients and seldom obviate tes ...

    STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Genomics MediaBook for a Technology Society

    SBC: CENTER LINE PRODUCTIONS            Topic: N/A

    DESCRIPTION (provided by applicant): The Genomics Revolution and the resultant explosion of knowledge in genomics are shaping our futures. Therefore, it is crucial that knowledge of genomics is broadly disseminated, so that future scientists, educators, policy makers, community leaders, and heads of households can harness the beneficial power of genomic science. Given the indiscriminate impact of ...

    STTR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Treatment for Septicemia Targets A1 ARs

    SBC: ENDACEA, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Septicemia is a medical syndrome characterized by an overwhelming systemic response to infection that can rapidly lead to shock, organ failure and death. In the U.S. septicemia is the 10th leading cause of death overall with over 750,000 cases and 215,000 deaths each year and accounts for $17 billion in annual health care expenditures. Following its release fr ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Generation of Human Hepatocytes

    SBC: IN VIVO TECHNOLOGIES            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to produce "humanized" livers in large animal models such as sheep and pigs that can serve as a reliable source of significant numbers of functional human hepatocytes. The isolated human hepatocytes and/or "humanized" livers can be used for drug toxicity studies as well as for possible clinical use in patients with liver failure. Tra ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. Pharmacotherapy for Opiate Addiction and Toxicity

    SBC: ION TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Morphine and other opiate drugs are widely used to treat severe pain but the addiction and side effects they produce often limit their use. The goal of this research is to develop a novel treatment for morphine addiction and toxicity based on an endogenous peptide, glycyl-glutamine (Gly-GIn). Gly-GIn is synthesized in brain from the opioid peptide, beta-endorph ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  8. QUANTITATIVE LC-MS DETECTION OF PEPTIDES IN CELIAC SPRUE

    SBC: LCMS LIMITED            Topic: N/A

    DESCRIPTION (provided by applicant): Celiac Sprue is an inherited disease of the intestine caused by ingestion of immunogenic peptides derived from gluten, a class of proteins present in wheat, barley and rye and therefore in many commercially available foods. Symptoms are severe, the only feasible treatment for Celiac Sprue being a strict adherence to a gluten free diet. This work seeks support f ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. Plasma Diagnostic for Alzheimer's Disease Pathology

    SBC: SAMARITAN PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Presently, there exists no simple minimally invasive test, such as a blood test, that can differentiate patients affected by Alzheimer's disease (AD) from healthy individuals. Our long-term goal is to develop new strategies for determining prognosis or predicting response to therapy. This will provide tools to improve clinical decision-making in the care of AD ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  10. SP004, a sigma-1 ligand with AchE inhibition properties

    SBC: SAMARITAN PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The acetylcholinesterase inhibitors (AchEI) are currently the most broadly used drugs to treat AIzheirmer's disease (AD). Unfortunately none of the beneficial effect lasts for more than a short two years time period, probably due to the progressive degeneration of the cholinergic neurons. This indicates that aiming at the same time at another target distinct to ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
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