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The Award database is continually updated throughout the year. As a result, data for FY22 is not expected to be complete until September, 2023.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Novel commensal polysaccharide treats multiple sclerosis through Treg modulation

    SBC: SYMBIOTIX BIOTHERAPIES, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Multiple sclerosis MS is a chronic demyelinating inflammatory disease that is the most common neurological disease of young adults affecting over patients in the US and over million patients worldwide MS is a disease of high unmet medical need currently treatable with one of twelve FDA approved drugs all of which result in either significant i ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Nonlinear Computation Tool to Chart Trajectories of Bipolar Disorder

    SBC: Biomedical Development Corporation            Topic: 103

    DESCRIPTION provided by applicant Bipolar disorder BD is a complex chronic illness characterized by recurrent often dramatic mood changes Self management of BD is an important component of treatment but is likewise complex and can be fraught with difficulties including misunderstanding of the condition and a lack of self awareness Combined with the nationwide shortage of mental healthcare ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Phase IIB: Portable Device for Telecare Monitoring of Elderly People

    SBC: BioSensics LLC            Topic: NIA

    DESCRIPTION provided by applicant We propose to further develop field test and commercialize a reliable and robust sensor technology that allows the objective assessment of daily physical activity risk of falling frailty and activity organization among older adults in he home and community This is a Phase IIB STTR application During Phases Iandamp II BioSensics LLC in collaboration wit ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Unbiased longitudinal neuromorphometry for clinical decision support

    SBC: CORTICOMETRICS LLC            Topic: NIA

    Project Summary Normal human neuroanatomy is incredibly variable, and increases with age. This impedes the ability of neuroimaging to detect effects in neurological conditions such as Alzheimerandapos;s disease (AD), Huntingtonandapos;s disease (HD), multiple sclerosis (MS) and schizophrenia. Most of the recently available state-of-the-art quantitative imaging tools still use cross-sectional metho ...

    STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  5. Microfluidic Processing of Leukocytes for Molecular Diagnostic Testing

    SBC: GPB Scientific, Inc.            Topic: 102

    DESCRIPTION provided by applicant The goal of this Phase II project is to optimize and validate a microfluidic chip based process that automates and shortens the labeling washing and collecting of human blood leukocytes WBCs for flow cytometric analysis of clinically important cell surface and intracellular markers Multi parameter flow cytometry is an increasingly powerful and widely used t ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Mixed Elpasolite Scintillators

    SBC: Radiation Monitoring Devices, Inc.            Topic: DTRA18B003

    The goal of this program is to develop the mixed elpasolite scintillators in order to achieve an energy resolution of  (≤ 2.5% (approaching 2%) at 662 keV for crystal sizes of up to 2 inch by 2 inch.  In this project we will investigate compositional changes in selected mixed-elpasolite(s) in order to achieve very high energy resolution.  By incorporating 6Li, neutron detection will also be t ...

    STTR Phase II 2020 Department of DefenseDefense Threat Reduction Agency
  7. Point of care blood coagulopathy diagnostics

    SBC: Coalesenz Inc.            Topic: DHA19A001

    We have developed a novel low-cost, multi-functional blood coagulation sensor that can measure a patient’s coagulation status within less than 10 minutes using a 25mL drop of blood. This device addresses the critical unmet need to identify and manage patients with an elevated risk of life-threatening bleeding or thrombosis, the major causes of in-hospital preventable death. In addition, our inno ...

    STTR Phase II 2020 Department of DefenseDefense Health Agency
  8. Urbanscape: Single Shot Multi-Task 3D Reconstruction

    SBC: Dzyne Technologies Incorporated            Topic: DTRA18B001

    Hazard assessment tools that model the transport and dispersion of Chemical, Biological, Radiological, Nuclear and Explosive (CBRNE) materials through urban areas are only as good as the 3D models that inform the physics model. Maintaining accurate, up-to-date 3D models of urban areas is challenging. Even in the commercial world, urban construction and demolition may result in the models created a ...

    STTR Phase II 2020 Department of DefenseDefense Threat Reduction Agency
  9. High Energy Resolution Mixed-Halide Elpasolite Scintillators for Next Generation RIID

    SBC: CapeSym, Inc            Topic: DTRA18B003

    The ability to discriminate between threatening and benign sources depends on the sensitivity, accuracy, and identification speed of the detection equipment. High energy resolution of the radionuclide sensor is necessary to decrease the likelihood of false identification. However, few scintillators achieve better than 3% energy resolution at 662 keV, and none exceed 2.5%. The goal of this effort i ...

    STTR Phase II 2020 Department of DefenseDefense Threat Reduction Agency
  10. Discrete 3-D Electronics for Mobile Radiation Detection Systems

    SBC: Radiation Detection Technologies, Inc.            Topic: DTRA18B002

    Phase II will utilize knowledge gained from phase I work to develop and execute a manufacturing process suitable for producing quantities of 3-D printed discrete circuits for radiation detection systems.  The goal is to support mobile radiation detection system requirements for high voltage, analog amplification, and MCA functionality to produce differential pulse height spectra in time sequence. ...

    STTR Phase II 2020 Department of DefenseDefense Threat Reduction Agency
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