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SBC: Oui Therapeutics, LLC Topic: NIMH
ABSTRACT Suicide is one of the top ten causes of death in the US and suicide rates have increased steadily over the last twenty years. Currently, the most effective treatment options are cognitive behavioral therapies for suicide prevention (CBT-SP), which have been shown to reduce both suicide attempt (SA) risk and suicide ideation (SI). However, access to these treatments is limited because ther ...STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
SBC: Biomedical Development Corporation Topic: NIDA
PROJECT SUMMARY / ABSTRACTThe opioid crisis is an epidemic with devastating health, social, and economic consequences for the United States. From 1999–2018, almost 450,000 people died from an overdose involving any opioid, including prescription and illicit opioids. Three million US citizens and 16 million individuals worldwide have had or currently suffer from opioid use disorder (OUD). The tot ...STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
SBC: Tier 1 Performance Solutions, LLC Topic: DHA17B002
According to the Joint Commission, approximately 70% of sentinel events in medical care are related to communication mishaps, and despite regular and frequent occurrence, poor communication during patient handoffs (i.e., transfer of patient care information, responsibility, and authority from one provider to another) remains a major contributor to medical errors (Nether, 2017; The Joint Commission ...STTR Phase II 2021 Department of DefenseDefense Health Agency
SBC: SIGNAL SOLUTIONS, LLC Topic: 100
EpiZode: Noninvasive Seizure Screening in Preclinical Models of Epilepsy There is an urgent need for research into treatment options for epilepsy and other seizure disorders. Animal models are increasingly used to understand disease mechanisms and to screen promising therapeutic approaches. Animal epilepsy model use typically requires expensive and labor-intensive experimentation, with invasive EE ...STTR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
Technology transfer of behavioral economic tasks for assessing alcohol reinforcer pathology: Development and feasibility of a commercially-available tool for clinical practiceSBC: BEAM Diagnostics, Inc. Topic: 270
PROJECT SUMMARY Alcohol use disorder (AUD) contributes to excessive disability, morbidity, and mortality in the United States. As one of the nation’s leading causes of death, public health guidelines recommend consistent standardized alcohol screening. However, screening for alcohol misuse is underperformed, laborious, and is susceptible to demand characteristics and concerns about stigmatizing ...STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
SBC: Biomedical Development Corporation Topic: 103
DESCRIPTION provided by applicant Bipolar disorder BD is a complex chronic illness characterized by recurrent often dramatic mood changes Self management of BD is an important component of treatment but is likewise complex and can be fraught with difficulties including misunderstanding of the condition and a lack of self awareness Combined with the nationwide shortage of mental healthcare ...STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
SBC: SUMMIT BIOMEDICAL IMAGING LLC Topic: 102
Project Summary/Abstract Counterintuitively, the incidence and societal impact of oral and oropharyngeal cancer are increasing in the US despite the markedly decreased use of tobacco products. This trend is exacerbated by the fact that almost two- thirds of patients have lymph node or distant metastases at the time of diagnosis, dramatically reducing 5-year survival rates. Oral cavity cancers are ...STTR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
SBC: ZANSORS LLC Topic: NIMHD
ABSTRACT Obstructive sleep apnea OSA is the most common type of sleep apnea OSA affects an estimated million adults and of all children in the US OSA results in tiredness depression and fatigue and has several associated common comorbidities It is believed that over of OSA remains undiagnosed The prevalence of OSA increases with age and if untreated increases the risk of ...STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
SBC: GPB Scientific, Inc. Topic: 102
DESCRIPTION provided by applicant The goal of this Phase II project is to optimize and validate a microfluidic chip based process that automates and shortens the labeling washing and collecting of human blood leukocytes WBCs for flow cytometric analysis of clinically important cell surface and intracellular markers Multi parameter flow cytometry is an increasingly powerful and widely used t ...STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
SBC: NOVATEUR RESEARCH SOLUTIONS LLC Topic: DTRA19B002
This STTR Phase II project proposes development of a statistical relational learning framework for identification of the function of laboratory equipment from imagery. The proposed framework uses semantic reasoning to incorporate evidence from multiple classifiers and feature extractors, domain knowledge, and scene context for scene understanding and labeling. The Phase II effort will focus on dev ...STTR Phase II 2021 Department of DefenseDefense Threat Reduction Agency