Award Data

Protection of deployed ground forces from disease-carrying insects requires the immediate and safe use of insecticides. Currently, control products are too slow to manage target pests and are unrealistic solutions under battlefield conditions. Vector-borne diseases transmitted by insects, such as malaria, dengue and leishmaniasis, are increasing worldwide and are more of a threat to our military f ...

Adenoviruses are a frequent cause of epidemic acute respiratory disease (ARD) in military recruit training centers and pose a significant threat to military readiness, especially during times of large mobilization. There are no FDA-licensed treatment options available for adenovirus infections. Under the SBIR phase I, PaxVax successfully re-developed research-grade Ad4 and Ad7 capsule vaccines wit ...

Lyme disease is the most common tick-borne disease in North America and one of the fast-growing infectious diseases in the United States.An inexpensive, portable and accurate diagnostic device for the detection of Borrelia bacteria in the deer tick will be developed.The diagnostic device will consist of an efficient extractor for disrupting the hard exoskeleton on the tick, an ultra-sensitive late ...

Typical handheld medical ultrasound array probes are not well suited to point of injury care or attended casualty evacuation vehicles due to their bulky size and the requirement that the device be held in the hand of the medic. Portable ultrasound systems are available that allow for improved mobility, but a truly wearable portable system has not yet been realized. This proposal seeks to develop a ...

This proposal is for a subsequent Phase II for the SBIR project Apps for Rapid Epidemiological Surveillance (AREA).Our Phase II accomplishments focused on AREA handheld apps and their use for managing epidemiological data acquisition.Our proposed subsequent Phase II effort will increase the AREA capabilities for data stream integration and decision support by extending the system to a Disease Outb ...

VecTOR Test Systems, Inc. will develop assay for rapid detection of the Lyme disease pathogen Borrelia burgdorferi in ticks in a field setting. In Phase I prototype assays to detect Borrelia burgdorferi were developed that met Phase I objectives. The development work will continue in Phase II in which the assay with the required sensitivity and specificity will be completed and evaluated in the la ...

including validation of cell extraction using standard assays and methods, and determination of the performance metrics. In addition, POC will develop a technology transition plan, FDA approval strategy, and a manufacturing plan for Phase III implementation.

ChromoLogic LLC (CL) is developing a Spectroscopic System for Therapeutic Drug Monitoring (THERASPEC), to meet the Armys need for a compact, robust system to assess the peak and trough therapeutic drug concentrations in blood to provide real-time TDM in fixed and field medical facilities. The THERASPEC prototype is based on spectroscopic

The focus of this effort is to enable the deployment of patient-centric and context-aware networked medical systems. Securing medical device communications is a foundational requirement before the Medical Internet of Things can become a reality. Devices and applications need to be provisioned with certified credentials; they need to discover each other through a secure discovery process; and mecha ...

On-demand cell and tissue samples are critical for both mass trauma care and advanced personalized medical procedures and continue to grow in importance. Biological tissue banks to support these on-demand applications lack safe and effective long-term storage methods. Current cryopreservation techniques and protocols use toxic cryoprotective agents that prevent successful full viability recovery o ...