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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Arenavirus Antiviral Lead Optimization

    SBC: ARISAN THERAPEUTICS INC            Topic: NIAID

    DESCRIPTION provided by applicant Arenaviruses comprise a diverse family Several species are associated with severe arenaviral hemorrhagic fever AVHF in humans that exhibit case fatality rates as high as Human infection with arenaviruses typically occurs through contact with materials contaminated with the excretions of an infected rodent although direct human to human transmission may ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Arrayed drug microinjection for guiding precision medicine in relapsed lymphoma

    SBC: PRESAGE BIOSCIENCES, INC.            Topic: 102

    DESCRIPTIONprovided by applicantImprovements in cancer diagnostics and therapeutics have positively impacted outcomes for oncology patients within select clinical nichesHoweversignificant therapeutic uncertainty awaits the majority of today s oncology patients who present in the clinic with cancer that will relapse after exhibiting an initial response or whose cancer is already refractory to stand ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Advanced morphological analysis of cerebral blood flow for acute concussion diagnosis and return to play determination

    SBC: Neural Analytics, Inc.            Topic: 101

    Project Summary Abstract Between and million people each year suffer a mild TBI in the US alone Reliable diagnosis and prompt treatments are vital to managing the often serious short and long term sequelae resulting from mild TBI However a reliable objective and accurate method for mild TBI diagnosis outside of a hospital setting and in particular for determining RTP readiness has e ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  4. An immune based approach for HIV eradication

    SBC: RETROVIROX, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Viral reservoir eradication has become a leading subject in the field of HIV research A plethora of antiretrovirals ARVs are available to efficiently treat infection Living with HIV has become a chronic disease in which viral load can be controlled in over ninety percent of patients Yet the health social and economical burden of the disease are unpre ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Near patient molecular diagnostics test for infections

    SBC: GeneFluidics, Inc.            Topic: R

    ABSTRACT Currentlythere are no FDA cleared molecular based tests for urinary tract infectionUTIpathogen identification and antimicrobial susceptibility testing to replace the andapos gold standardandaposof dipstick urinalysis and urine culturingAll pathogen identification tests still rely on clinical isolates from urine cultureslargely unchanged from Kochandapos s postulates developed in theth cen ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Rapid Immunodiagnosis of Drug-Resistant Bacterial Pathogens

    SBC: SILVER LAKE RESEARCH CORPORATION            Topic: NIAID

    PROJECT SUMMARY ABSTRACT This proposal describes Phase II of the development of a rapid immunoassay test kit for the determination oflactam antibiotic resistanceto be used as a point of care diagnostic test for urinary tract infectionsTodayantibiotics for UTI are prescribed empiricallywith no diagnostics available to clinicians to avoid treating resistant infections with the very drug to which the ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Preclinical Testing of a Novel Flow Diverting Stent for Treating Intracranial Aneurysms

    SBC: NeuroSigma, Inc.            Topic: 101

    DESCRIPTIONprovided by applicantThe purpose of this project is to develop an improvedminimally invasive treatment for intracranial aneurysmsIntracranial aneurysms are spherical outpouchings of blood vessels in the head that result from weakness in the vessel wallUnruptured aneurysms are present in approximatelyof the general populationand rupture can be devastating with a high morbidity and mortal ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Cyanalyzer A Medical Laboratory Device for the Rapid Diagnosis of Cyanide Exposure

    SBC: SEACOAST SCIENCE, INC.            Topic: 106

    Project Summary The overall objective in the proposed project is to develop and test a prototype Cyanalyzer sensor designed for the rapid and accurate diagnosis of cyanide exposure The proposed device directly addresses a long term goal of the National Institute of Neurological Disorders and Stroke NIH Countermeasures Against Chemical Threats CounterACT program development of rapid diagnostic ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Strain Independent Therapeutic Antibodies for Influenza

    SBC: TRELLIS BIOSCIENCE, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Trellis Bioscienceandapos s CellSpotandquot technology for identification of rare human antibodies with high specificity and affinity against multiple antigen has enabled discovery of highly efficacious strain independent antibodies to Respiratory Syncytial Virus and to Cytomegalovirus We have now applied CellSpot to isolate two native human antibodies with ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Miniature, integrated and mass-producible fluorescence microscopes for in vivo brain imaging in freely behaving rodents

    SBC: Inscopix, Inc.            Topic: 101

    Project Summary There is increasing awareness that aberrant neural circuit activity is a core manifestation of many neuropsychiatric diseasesincluding autismschizophreniadepression and Alzheimerandapos s diseaseThis realization has opened tantalizing prospects for more powerful and precise therapeutic approaches based on retuning of abnormal circuit activityHoweverwe still lack crucial understandi ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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