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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A Method to Increase Buprenorphine Treatment Capacity and Effectiveness
SBC: CBT4CBT LLC Topic: R42The goal of this fast track STTR proposal is to expand buprenorphine maintenance therapy for opioid dependent patients Over million people in the US are addicted to opiates Providing effective agonist therapy methadone or buprenorphine coupled with behavioral counseling greatly improves outcomes reduces morbidity and reduces societal costs Methadone maintenance treatment has been limit ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
A simple and effective diagnostic test for gastrointestinal bleeding to improve patient outcomes
SBC: CUMBERLAND PHARMACEUTICALS, INC. Topic: 300DESCRIPTION provided by applicant Problem Lower gastrointestinal bleeding is a significant medical problem in the United States accounting for more than hospital admissions and tens of billions of dollars of healthcare spending annually It is common for bleeding from a single site to stop and restart multiple times The three modalities now used to diagnose and locate gastrointestina ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Controlled Release Polymer Structures for In Situ Chemical Oxidation of Contaminated Groundwater
SBC: AXNANO LLC Topic: NIEHSDESCRIPTION provided by applicant The EPA estimates that one out of every four Americans lives within three miles of a hazardous waste site Over brownfield sites are awaiting remediation and sites on the National Priorities List Potential Responsible Parties or the Superfund program are tasked with remediating these sites but insufficient funding and growing number of sites hav ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Developing a novel adjuvant system for therapeutic vaccines against lung cancer
SBC: FasCure Therapeutics LLC Topic: 102DESCRIPTION provided by applicant Therapeutics is focused on the development of adjuvant systems with desired immune activities for targeted indications The Companyandapos s immune stimulatory adjuvant platform builds on combinatorial use of immune agonists with distinct immune targets and mechanisms of action for the generation of therapeutic immune responses Critical to this platform techno ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of An Integrated High Throughput Imaging and Image Analysis Platform for Muscle
SBC: CytoInformatics LLC Topic: NIADESCRIPTION provided by applicant There is growing awareness that weakness of muscle is a significant biomedical health issue associated with many different chronic diseases and aging There are a variety of different diseases that affect muscle including muscular dystrophy fibromyalgia cerebral palsy amyotrophic lateral sclerosis and myasthenia gravis each of which carries its own uniqu ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of an Osteoinductive Spinal Fusion Implant for Enhanced Fusion Rates
SBC: EVOKE MEDICAL LLC Topic: NIAMSDESCRIPTION provided by applicant The objective of this Phase I STTR research is to develop and test osteoinductive lumbar spinal fusion implant prototypes made using materials technology developments discovered by the PI at the University of Kansas In preliminary work lower impedance piezoelectric composite materials that generate power for direct current DC electrical stimulation applica ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
development of immunodeficient rabbit models
SBC: Celetrix LLC Topic: NIAIDDESCRIPTION provided by applicant Transplantation of human or animal pluripotent stem cells PSCs or their derivatives to model animals constitutes an important preclinical system to model and investigate cell survival development and differentiation in vivo and to assess the safety and efficacy of transplantation based cell therapies Immunodeficient mice are dominantly used in biomedical ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Engineering a phosphotyrosyl-tRNA Synthetase
SBC: AXIOMX INC Topic: 300DESCRIPTION provided by applicant Although tyrosine phosphorylation is an important controlling element in cell signaling no tRNA suppressor for phosphotyrosine pTyr incorporation has yet been made We propose to use directed molecular evolution of several aminoacyl tRNA synthetases aaRSs to identify mutations that enable binding of pTyr to the aaRS Specifically ATP molecules will be att ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Expressing humanized bacterial luciferase in stem cells: Moving beyond firefly luciferase to expand the informational capacity of animal models for regenerative medicine
SBC: 490 BIOTECH INC Topic: 200DESCRIPTION provided by applicant This Small Business Technology Transfer STTR Phase I project proposes to develop autonomously bioluminescent human stem cells for continuous reagent free and real time bioimaging to address the National Institutes of Healthandapos s request for new techniques for non invasive long term tracking of stem cell survivability engraftment and migration followi ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Facile, High Throughput Aerosol Production of Oxidizer Particles
SBC: LUNA INNOVATIONS INCORPORATED Topic: DTRA14B001The Defense Threat Reduction Agency (DTRA) has been supporting research of energetic materials and incendiaries as payloads for weapons to defeat targets containing chemical and biological agents. Several universities and Navy labs have been involved in this research, and have narrowed down on a few material formulations that are efficient biocides. These formulations contain a chemical ingredient ...
STTR Phase I 2015 Department of DefenseDefense Threat Reduction Agency