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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Marburg Virus Prophylactic Medical Countermeasure

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: CBD18A002

    There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  2. Marburg Virus Prophylactic Medical Countermeasure

    SBC: Flow Pharma, Inc.            Topic: CBD18A002

    Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  3. Virus-Like Particle Based pan-Marburgvirus Vaccine

    SBC: Luna Innovations Incorporated            Topic: CBD18A002

    Marburg virus (MARV) is a filamentous enveloped non-segmented negative sense RNA virus. This viruse is considered to be extremelydangerous with case fatality rates as high as 88-90%. Extensive efforts have gone towards effective vaccines for MARV prevention, however,none have been successfully established as licensed vaccines. Glycoprotein (GP) is the only surface protein of MARV. There are substa ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  4. Novel Circulating RNA-based Markers as Diagnostic Biomarkers of Infectious Diseases

    SBC: CFD Research Corporation            Topic: CBD18A001

    In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

    STTR Phase I 2018 Department of DefenseOffice for Chemical and Biological Defense
  5. Robust Molecular Predictive Methods for Novel Polymer Discovery and Applications

    SBC: Sheeta Global Tech Corp.            Topic: 08b

    This Small Business Technology Transfer (STTR) program aims at development and demonstration of an integrated theoretically/experimentally combinatorial method for the accurate prediction of rheological behaviors of special polymer solutions. In-depth understandings of dynamic responses of the polymer solutions under external shear are essential for development of the “smart” polymer-based add ...

    STTR Phase II 2018 Department of Energy
  6. Compact Laser Drivers for Photoconductive Semicond

    SBC: SCIENTIFIC APPLICATIONS & RESEARCH ASSOCIATES            Topic: DTRA16A004

    For effective protection against radiated threats, it is important to understand not only the physics of the threats, but also to quantify the effects they have on mission-critical electrical systems. Radiated vulnerability and susceptibility testing requires delivery of high peak power and peak electric fields to distant targets. The most practical solution to simulate such environments on large ...

    STTR Phase II 2018 Department of DefenseDefense Threat Reduction Agency
  7. Hierarchical, Layout-Aware, Radiation Effects Tools Vertically Integrated into an EDA Design Flow for Rad-Hard by Design

    SBC: Reliable MicroSystems, LLC            Topic: DTRA16A003

    The goal of this workis to establish a radiation-aware capability in a commercial EDA design flow that will enable first-pass success in radiation resiliency for DoD ASIC designs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications.Such an integrated capability does not presently exist.The ...

    STTR Phase II 2018 Department of DefenseDefense Threat Reduction Agency
  8. A Blockchain-enabled Peer-to-Peer Energy Trading Platform for Managing Complex Exchange of Kilowatt-hours and Negawatts

    SBC: BEMCONTROLS, LLC            Topic: 12c

    The structure of the electric utility business has long been a centralized model where an electric utility is the only authority selling electricity to, and buying excess rooftop PV generation, from customers. This is changing as utilities explore new business models including Distributed System Operator (DSO) models. On the other side of the meter, with the increasing penetration of rooftop solar ...

    STTR Phase I 2018 Department of Energy
  9. Very High Field Hybrid Superconducting Magnet Using Bi-2212

    SBC: Cryomagnetics, Inc.            Topic: 26b

    Hig e and advanced materials are continually demanding higher magnetic fields. Efforts to generate fields in excess of 25 Tesla have been a principal driver of high temperature superconductor research. Although HTS materials were discovered decades ago and have always shown significant potential for high field use, until recently magnets using the technology have remained elusive. Great progress h ...

    STTR Phase I 2018 Department of Energy
  10. High Quantum Efficiency Uni-Traveling-Carrier Photodiode for Optical to Microwave Transduction

    SBC: Freedom Photonics LLC            Topic: 29d

    Modern quantum information systems employ optical photons for long distance communication, operating at ambient temperature, between microwave cavities, which house microwave photons used in quantum computing and microwave detection. These optical photons, carried by fiber-optic or free-space links, offer a low-cost, uncooled alternative to bulky, expensive microwave coaxial cables, which are loss ...

    STTR Phase I 2018 Department of Energy
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