Award Data

The primary objective of this effort is to develop a tractable computational tool to assess the probability of ignition within aircraft combustors and augmentors during routine igniter and/or system design analysis. This computational tool will provide for the off-line assessment of ignition probability given flowfield simulation data, characteristic igniter geometric and physical parameters, and ...

The Candent Technologies “Reduced Cavitation, High Efficiency Outboard Propulsor for Small Planing Craft” Phase II program is structured to develop an advanced waterjet propulsor for the Combat Rubber Raiding Craft (CRRC). This new axial flow waterjet propulsion system is designed as a “bolt on” assembly that replaces the lower unit of the existing MFE 55 outboard motor. This new propulsio ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

Oceanit proposes to research and develop chemical or non-chemical methods and processes to impart surface morphology modifications to aluminum-magnesium (Al-Mg) alloys to mitigate and increase the exfoliation corrosion resistance.

In a pandemic or exposure to weaponized Marburg virus the morbidity, mortality and social unrest that will ensue before vaccines orMilitary operating on foreign soil as well as to the population of the US Homeland. Practically all threat agents of biological origin (except forcertain non-proteinaceous toxins, typically produced by marine organisms and fungi) have their structure and vital function ...

Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

In resource limited settings, rapid and accurate diagnosis of infections is critical for managing potential exposures to highly virulent pathogens,whether occurring from an act of bioterrorism or a natural event. This is especially important for hard to detect intracellular bacterial andalphavirus infections, that overlap symptomatically and often treated empirically due to a lack of reliable and ...

Traditional approaches to accelerated fatigue testing rely on heuristic methods with thresholds based mostly on experience and engineering judgment. These methods generally do not apply to the multiaxial dynamic loading situations characteristic of most aerospace applications and often result in uncharacteristic fatigue damage and failure modes during testing. To overcome the limitations of tradit ...

Filamentation of ultra-short laser pulse propagation in non-linear media offers significant potentials allowing to address numerous problems in military and commercial sectors. However, practical implementation of this requires an ability to control the USLP at its propagation through inhomogeneous media, like turbulent atmosphere. On the basis of our approach for combating turbulence effects on p ...

Areté proposes the development of Q-switched semiconductor lasers that can be scaled to produce high output peak powers within the blue/green wavelength band. The proposed system will utilize nanostructure quantum wavefunction engineering for gain material designs having extended excited state lifetimes and suppressed non-radiative processes to enable energy storage for high-peak-power optical pu ...