Award Data

The broader impact/commercial potential of this Small Business Innovation Research Phase II project will combine computational protein engineering (CPE) software, tools and methods into a "platform technology" that enables new products and technologies in a wide range of scientific areas, including industrial enzymes, pharmaceuticals, therapeutics, medical diagnostics and bioenergy. This project w ...

Leveraging the results of our Phase I work, the Torch Team proposes to execute laboratory-based experiments to elucidate fundamental micro-debris formation mechanisms to improve optical modeling of impacts. Optical signatures from impacts collected over the last decade have identified definitive micro-debris parameter trends. However, current theories have difficulty reproducing these optical ob ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to lower manufacturing costs in the photovoltaic (PV) industry. In the past decade, the solar energy industry has seen double digit compound annual growth rates. This success has resulted in the industry consuming nearly 10 percent of the global silver production. The cost of metalliza ...

This STTR Phase I project represents a revolutionary advance in adaptive educational systems for computer programming by using big data collected from previous coding exercises to automatically generate hints and feedback for students coding in an integrated development environment (IDE). This work addresses NSF's Educational Applications subtopic "Tools for Learning and Assessment" by making adap ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is far-reaching. A preliminary market study indicates that 1.5% to 2.5% of the developed world?s population suffers from heart arrhythmias while the WHO reports ~0.5% of the global population. For Atrial fibrillation, in the USA alone this disease will afflict ~7.7 million people by 2015, affl ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project is the development of a widely deployable, inexpensive and accessible diagnostic platform that can rapidly detect infectious diseases in clinical and non-clinical locations, including settings with minimal infrastructure. While the platform technology itself is applicable to the detection of a wide nu ...

This Small Business Innovation Research Phase I project addresses the need for obtaining sustainable sources of chemicals and fuels. This proposal aims to solve the problem in the context of a chemical with uses in high performance polymers with total addressable market in excess of $7 billion per year. A key requirement of such processes is high efficiency of conversion for economic viability. We ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to shift current practices in bone fracture fixation care from using permanent metal implants to biodegradable metal implants (screws, plates, pins, rods, etc.). A promising biodegradable metal that is gaining widespread attention is magnesium. This project will advance magnesium implant te ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to overcome limitations that prevent effective treatment of major wound infections. The U.S. spends over $50 billion per year on wound care; thus there is a large potential market for this product. Current wound care products have a high risk of rejection, scarring, and antibiotic resistanc ...

This Small Business Technology Transfer Phase I project will develop phage-based colorimetric sensors to provide cost-effective, low-powered detection and quantification of natural gas. Currently, there is no technology that can reliably detect early natural gas leaks on-site in real-time; existing solutions are either not sensitive enough (handheld infra-red detector) or too bulky (gas chromatogr ...