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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Whole Ovary Vitrification for Fertility Preservation

    SBC: 21st Century Medicine, Inc.            Topic: NICHD

    The long term goal of this proposal is to develop a safeeffective and user friendly vitrification system for cryopreservation of whole human ovariesIn the U Sovergirls and women ageare diagnosed with cancer annuallyWhile improved diagnosis and treatment have led to increased survival ratesin premenopausal andin childhood cancer patientsdevastating side effects of cancer therapies include premature ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. SkillTalk: Communication Training around Sexual Health Topics for Parents of Youth with Autism Spectrum Disorder

    SBC: DFUSION INC.            Topic: NICHD

    ABSTRACT SkillTalkCommunication Training around Sexual Health Topics for Parents of Youth with Autism Spectrum Disorder Adolescents with Autism Spectrum DisorderASDface a range of impairments in social interaction and communication settingsincluding those involved with sexual communication and behaviorLike their neurotypical peersadolescents with ASD need comprehensive sexual education to learn an ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. A Smart Entry Needle System for Peritoneal Access and Insufflation during Laparoscopic Surgery

    SBC: Theranova LLC            Topic: NICHD

    AbstractIn themillion laparoscopic surgeries performed annually worldwideachieving peritoneal access for insufflation accounts for one third of the associated complicationsPeritoneal access is typically achieved using the Veress needleHoweverthe use of the Veress needle has been identified as the source ofof the complications associated with laparoscopic proceduresIt has been shown that complicati ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Ninja Theranostics for overcoming the drug delivery barriers to pediatric brain tumor

    SBC: THERANOSTEC INC            Topic: NICHD

    Ninja Theranostics for overcoming the drug delivery barriers to pediatric brain tumor Project Summary Abstract Pediatric brain tumorsPBTsare the leading cause of cancer related morbidity and mortality among childrenVincristineVCRhas been approved to treat PBTsbut its inability to cross blood brain barrierBBBblood brain tumor barriersBBTBand dose limiting neuropathy have greatly limited its clinica ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Administrative Supplement to restore fee funds

    SBC: AMERICAN LIFE SCIENCE PHARMACEUTICALS, INC.            Topic: NINDS

    Project Summary Traumatic brain injuryTBIcauses detrimental behavioral dysfunctions and brain neurodegeneration butunfortunatelythere currently is no effective pharmaceutical TBI treatmentThe underlying PhaseSTTR grant is to develop a new class of TBI drugs that inhibit the protease cathepsin BGenetically deleting the cathepsin B gene in mice results in substantial behavioral and pathology improve ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Senescence After Growth Arrest a new therapeutic modality for progeria

    SBC: Atropos Therapeutics, Inc.            Topic: NIA

    Abstract The long term goal of Atropos Therapeutics Incis development of a therapeutic drug for progeria and other aging related disorders based on their ability to regulate the senescence processAt the end of PhaseSBIRwe anticipate having two to five scaffolds that have utility slowing or preventing cellular senescence in tissue cultureIn phasewe anticipate moving scaffolds toward lead selectiont ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. Next generation in vivo miniature microscopes integrating dual-color imaging, 3D imaging, and optogenetic stimulation with a cloud-compatible data acquisition platform

    SBC: Inscopix, Inc.            Topic: 101

    Project Summary Our understanding of neuropsychiatric disorders is undergoing a paradigm shift away from simple models emphasizing neurotransmitter imbalance towards more sophisticated theories based on abnormalities in neural circuit functionThis is especially important for understanding disorders like Schizophrenia and PTSDwhich defy simple biochemical explanationsbut are now known to involve ab ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. A Novel Transurethral Cryotherapy Catheter System to Treat Benign Prostate Hyperplasia

    SBC: Theranova LLC            Topic: R

    Abstract Benign prostate hyperplasiaBPHis a chronic and highly prevalent medical condition in aging menApproximatelyof men agedyears are affected by BPH and associated lower urinary tract symptomsLUTSa progressive and chronic medical condition that drastically impairs quality of lifeWhile first line drug therapies successfully impede further enlargement of the prostate glandthey only provide modes ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel, Low-Cost Device to Guide Peripherally Inserted Central Catheter (PICC) Line Placement

    SBC: Theranova LLC            Topic: NIA

    Abstract Improper placement of peripherally inserted central cathetersPICCsis costly and has serious complications for critically ill patientsMore than one million PICCs are placed each year to provide IV therapieswhere navigation through the venous system is typically performed blindor without navigation guidanceAs a resultof PICC tips are not optimally placed on the first attempt and require rep ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Topical delivery of therapeutic aptamers

    SBC: APTITUDE MEDICAL SYSTEMS INC            Topic: NIBIB

    PROJECT ABSTRACTTopical delivery of therapeutic agents across skin offers key benefits in improving patient compliancelowering systemic drug exposureand enabling tunable deliveryTherapeutic macromolecules such as antibodies or aptamers enables better efficacyless off target effectsand longer half life comparing to small moleculesand may unlock tremendous additional value if delivered topicallyMult ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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