Award Data

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will provide the market with a novel non-invasive method for measuring fluid status in patients with congestive heart failure (CHF). The ability to detect volume status changes prior to the onset of heart failure symptoms has tremendous patient care and economic impact. According to the Americ ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to develop odorant receptor function bioassays to provide services for companies that develop and formulate odors used in many kinds of commercial products. These services identify the biological sensors responsible for specific odor sensations and determine how these sensors are invol ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to develop reliable technology for the production of aptamer pairs. Aptamers are core reagents in emerging markets, regarded as alternatives to monoclonal antibodies in therapeutics, diagnostics, and imaging. They possess several appealing qualities: Ease of in vitro synthesis, flexibl ...

The broader impacts of this Small Business Technology Transfer Phase I project relate to the increased viability of indigo as an agricultural crop competing with synthetically manufactured indigo dye. Indigo was among the major global cash crops of the 18th and 19th centuries and accounted for 100% of the indigo dye consumed in the world. Since the beginning of the 20th century, nearly 100% of the ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase II project, in which a non-invasive respiratory muscle stimulation device and approach to weaning patients from mechanical ventilation will be developed, is a reduction in public health care expenditure and a reduction in morbidity for the half a million patients who have difficulty weaning from mechani ...

Thermally induced fatigue and residual stress introduced during fabrication are sources of failure in microelectronics, which raises reliability concerns for MDA and its system integrators. CFDRC has teamed with experts in the reliability of microelectronics packaging to develop a physics based modeling and testing protocol to correlate material properties and thermal loading conditions to stress ...

The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

Establish a radiation-aware analysis capability in a commercial EDA design flow that will enable first-pass success in radiation-hardened by design (RHBD) for DoD ASICs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications. Layout-aware, calibrated single-event radiation models that captur ...

Control Theory tools and processes for analyzing the interactions of complex System of Systems (SoS) are lacking, specifically when sub-systems are independently designed and/or higher levels of SoS controls are applied. Integrating these sub-systems into the SoS, can result in dynamic interactions between these sub-systems and the SoS controls resulting in unexpectedly large deviations between ex ...

In this research effort, GTD Unlimited will design tools for efficiently specifying, representing, and analyzing the interactions between control systems in System of Systems (SoS). Our approach will be to model the problem as an uncertain system and analyze the resulting models using control methods. Control methods can be related back to the standard Nyquist criterion for stability, ensuring t ...