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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Optimization of sigma-2 receptor modulators for the treatment of cognitive dysfunction
SBC: COGNITION THERAPEUTICS, INC. Topic: NIAAbstractProject Summary Cognition Therapeutics IncsCogrxmission is to develop effective therapeutics for Alzheimer s diseaseADOligomers of the brain protein Amyloid betaA Oshave been identified as toxic components that are involved with disease progressionCognition has identified a subset of sigmareceptor binding modulators that displaces A Os from synaptic receptor sites and clears them into the ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Small Molecule Inhibitors of HIV Nef Virulence Factor for Treatment of HIV AIDS
SBC: FOX CHASE CHEMICAL DIVERSITY CENTER INC. Topic: 100DESCRIPTION provided by applicant While HIV AIDS can be managed with antiretroviral drugs these agents do not clear the virus and require life long administration Recently we discovered a completely new class of compounds that interfere with the HIV virulence factor called Nef This viral protein is critical to HIV replication in vivo immune escape of HIV infected cells and AIDS progre ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
SMALL MOLECULE ANTAGONISTS OF PF FOR THE TREATMENT AND PREVENTION OF HIT
SBC: FOX CHASE CHEMICAL DIVERSITY CENTER INC. Topic: NHLBIDESCRIPTION provided by applicant We have discovered the first ever inhibitors of PF a platelet protein central to the pathophysiology of heparin induced thrombocytopenia HIT Heparin is a naturally occurring anticoagulant that prevents the formation of clots and extension of existing clots within the vasculature and major medical applications of heparin include dialysis cardiac catheteri ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Automated Object Contouring Methods and Software for Radiotherapy Planning
SBC: Quantitative Radiology Solutions LLC Topic: 102Abstract In 2015, 1,658,370 new cancer cases are estimated to occur in the US, where nearly two-thirds will have radiation therapy (RT). Given that there are over 2,300 RT centers in the US, and current systems for contouring organs at risk (OARs) rely mostly on manual methods, there is a strong commercial opportunity for producing a software system that can contour OARs in medical images at a hig ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Wireless sensor and telemedicine to screen for sleep apnea in elderly adults
SBC: ZANSORS LLC Topic: NIMHDABSTRACT Obstructive sleep apnea OSA is the most common type of sleep apnea OSA affects an estimated million adults and of all children in the US OSA results in tiredness depression and fatigue and has several associated common comorbidities It is believed that over of OSA remains undiagnosed The prevalence of OSA increases with age and if untreated increases the risk of ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Measuring Bladder Permeability with MRI Using a Novel Contrast Agent Formulation
SBC: Lipella Pharmaceuticals Inc. Topic: 300ABSTRACT This Phase II SBIR proposal leverages the progress made in Phase I on the development of a novel contrast mixture enhanced Tweighted MRI technique as a safesensitiveand objective diagnostic test for the increased permeability in the luminal surface of the urinary bladder in Interstitial Cystitis Bladder Pain SyndromeIC BPSpatientsThe purpose of having such a test is ultimately to allow cl ...
STTR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health -
Development of novel research tools and a database for mapping human mitochondrial tRNA modifications by mass spectrometry
SBC: Ribonova Inc. Topic: R42Summary In this fast track Phase I II STTR project a novel mass spectrometry method and a matched reagent kit will be developed for mapping modified nucleotides in human mitochondrial transfer RNA mt tRNA including the most abundant modification pseudouridine which hitherto has proved to be a technical challenge because it is an isomer of uridine These new research tools will be harnessed to build ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Hierarchical, Layout-Aware, Radiation Effects Tools Vertically Integrated into an EDA Design Flow for Rad-Hard by Design
SBC: RELIABLE MICROSYSTEMS LLC Topic: DTRA16A003The goal of this workis to establish a radiation-aware capability in a commercial EDA design flow that will enable first-pass success in radiation resiliency for DoD ASIC designs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications.Such an integrated capability does not presently exist.The ...
STTR Phase II 2018 Department of DefenseDefense Threat Reduction Agency -
A brief iPad based screening measure for HIV associated neurocognitive disorders
SBC: Digital Artefacts LLC Topic: 105Despite significance advances in anti retroviral treatments HIV associated neurocognitive disorder HAND remains prevalent and can affect a broad range of everyday activities An effective brief cognitive screen that could be implemented in busy HIV clinics where clinicians have limited time to provide care for patients with complex medical psychiatric and cognitive conditions has the poten ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of An Integrated High Throughput Imaging and Image Analysis Platform for Muscle
SBC: CytoInformatics LLC Topic: NIADESCRIPTION provided by applicant There is growing awareness that weakness of muscle is a significant biomedical health issue associated with many different chronic diseases and aging There are a variety of different diseases that affect muscle including muscular dystrophy fibromyalgia cerebral palsy amyotrophic lateral sclerosis and myasthenia gravis each of which carries its own uniqu ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health