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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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AFM based nanoscale IR Spectroscopy (AFM-IR) as a characterization platform for P
SBC: Anasys Instruments Corp. Topic: 300DESCRIPTION provided by applicant Anasys Instruments and Prof Lynne Taylor of Purdue propose to develop nanoscale chemical characterization capabilities for drug formulation research This project will build on successful Phase I research demonstrating feasibility of atomic force microscope based infrared spectroscopy AFM IR in pharmaceutical applications This Phase II research will advance ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Non-Dispersive Reaction and Separation Processes for Pharmaceutical Synthesis
SBC: CHEMTOR, L.P. Topic: 300DESCRIPTION provided by applicant A number of pharmaceutical reactions and wash processes involve interaction between immiscible phases within reactors or extraction equipment Multi phase synthesis processes have been traditionally been carried out through dispersion of one of the phases into the other in the form of droplets Such arrangement increases the surface area of interaction thereby ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Green Algal Strains for Biological Control of West Nile Virus Mosquitoes
SBC: Pond Life Technologies Limited Liability Company Topic: NIAIDDESCRIPTION provided by applicant West Nile virus WNV has become endemic to the US with yearly infection peaks coinciding with the activity of its mosquito vector was the worst year for WNV since with deaths and estimates of non neuroinvasive cases There is no specific treatment or vaccine so mosquito control is the only approach available Fortunately controll ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A hormonal therapy for preeclampsia
SBC: ADEPTHERA, LLC Topic: NICHDDESCRIPTION provided by applicant Preeclampsia is a pregnancy specific hypertensive disorder that can lead to multi organ failure seizure and maternal death Preeclampsia is also responsible for as many as of premature births in the United States Although better neonatal care has improved the likelihood of preterm babies surviving many face increased mortality and serious long term mor ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A Protective Tetravalent Vaccine Candidate for Dengue Fever Virus
SBC: ALTRAVAX, INC Topic: NIAIDDESCRIPTION provided by applicant There are approximately million cases of dengue fever each year with billion people at risk mostly in low income countries There are four serotypes of dengue fever virus DENV and in its uncomplicated form the disease is worthy of its indigenous name andquot break bone feverandquot An individual may suffer sequential infections with multiple DE ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Engineering a phosphotyrosyl-tRNA Synthetase
SBC: AXIOMX INC Topic: 300DESCRIPTION provided by applicant Although tyrosine phosphorylation is an important controlling element in cell signaling no tRNA suppressor for phosphotyrosine pTyr incorporation has yet been made We propose to use directed molecular evolution of several aminoacyl tRNA synthetases aaRSs to identify mutations that enable binding of pTyr to the aaRS Specifically ATP molecules will be att ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A high-throughput kit for detection of RNA modifications
SBC: MAVERIX BIOMICS, INC. Topic: NIDADESCRIPTION provided by applicant The broad objective of this project is to develop an integrated wet lab dry lab kit for high throughput detection of RNA modifications The final product will provide all required molecular biology reagents a set of simple and robust experimental manipulations for facile analysis of modifications and researcher friendly analytic cloud based software requi ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Development of a Broad Spectrum Antiviral for Ebola and Marburg viral Infections
SBC: Omm Scientific, Inc Topic: NIAIDDESCRIPTION provided by applicant The long term goal of this project is to gain FDA approval for commercialization of a broad spectrum small molecule antiviral agent that is effective in treating Ebola virus EBOV and Marburg virus MARV These pathogens are major biothreat agents for which there are no approved therapeutic options or vaccines The developed drug will inhibit a conserved hum ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Rapid Diagnostics for Mucormycosis
SBC: VITALEX BIOSCIENCES, LLC Topic: NIAIDDESCRIPTION provided by applicant Mucormycosis most commonly caused by Rhizopus oryzae is a life threatening infection that occurs in patients immunocompromised by diabetic ketoacidosis DKA neutropenia corticosteroid use and or increased serum iron Because of the rising prevalence of these risk factors the incidence of mucormycosis has risen Despite disfiguring surgery and aggressive ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Lactoferrin Modulation of Granuloma Pathology
SBC: Pharmareview Corporation Topic: NIAIDDESCRIPTION provided by applicant Host immunity plays a major role in development of Tuberculosis disease Tuberculosis infected individuals respond by formation of granulomas which contain bacilli However organisms within granulomas are protected from the full scope of immune mediated defenses We hypothesize that modulation of destructive immune mediated pathology while preserving essent ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health