Award Data

To address the Chemical and Biological Defense programs (CBDs) need for medical countermeasures against mycotoxin intoxication, PhysicalOptics Corporation (POC) proposes to develop a new Mycotoxin Neutralization Treatment (MyNT). This proposed solution is based on neutralizingmycotoxin from its deleterious effects by acting on multiple levels of mycotoxin metabolism through the novel combination o ...

Aflatoxins are a paradigm among fungal produced mycotoxins that are present in food supplies and are strongly associated with increased risk forthe development of hepatocellular carcinoma. Currently, there are no known countermeasures that can selectively mitigate aflatoxin toxicity andthe available options are only symptomatic treatments. To meet this challenge, we propose to harness the microbio ...

DHP is seeking new image compression technologies that will retain diagnostic quality and reduce the burden of digital medical image transmission on the militarys tactical networks.ATA is proposing to tailor the latest state-of-the-art commercial image compression algorithm, the Main Still Picture Profile of the High Efficiency Video Coding (HEVC) standard, for medical imagery.HEVC has been shown ...

Based on encouraging Phase I feasibility results, we propose developing a novel gene therapy approach to promote guided vascular regeneration in treating extremities after traumatic injury. Our approach is to provide thread-like implants comprised of aligned nanofibrillar collagen scaffolds loaded with Hepatocyte Growth Factor (HGF) vectors (e.g., HGF DNA plasmid, modified mRNA) designed to enhanc ...

Based on our success in developing the world first commercial high energy femtosecond fiber laser system and our leading proprietary technology development in ultrashort pulsed fiber laser material processing, PolarOnyx proposes, for the first time, a compact high energy fiber laser based smart wound healing tool to meet with the requirement of this DHP solicitation. It includes a high energy fs f ...

SummaryUnmanned aircraft systems (UAS) and small UAS (SUAS) technology hold great promise for facilitating the management of wildfires on forest lands. However technology is only a small part of the problem of integrating UAS into fireground operations. Significant concerns must be addressed about the coordination of air assets in the high-risk operational wildland fire airspace environment, which ...

The southern pine beetles, which can kill thousands of trees in epidemic attacks, had never been found beyond the pitch pine forests of the American South, because the winters were too cold. But they have migrated to New Jersey, where they have destroyed more than 30,000 acres of forest since 2002. And, according to a recent report of the New York Times, the warmer winters have now beckoned them t ...

Thisprojectis designed to enable Catalina Sea Ranch (CSR)to utilize and improve upon the results of recentacademic researchintocryopreservation ofmussellarvaeas applied to large-scale commercial sustainable shellfish aquaculture operations, and to initiate efforts to successfully cryopreserve mussel sperm and oocytes. The ability to storecryopreserved mussel larvae over long periods andachieve a h ...

The world needs more seafood, yet the ocean's wild fish stocks simply cannot meet this burgeoning demand. Globally, 85% of our commercial stocks have already been fished to their biological limit. These heavily exploited wild marine fish stocks are under increasing pressure, with growing global population (projected to reach 9 billion by 2050, including concurrent expansion of the middle class ...

The proposed Phase I project includes (i) utilizing Global Algae Innovations low-cost production technology to generate a new algal feed ingredient that is a combination of the new algae strain and a high omega-3 diatom algae; and (ii) evaluating the new algal feed ingredient through compositional analysis, a rainbow trout fry trial, and a digestibility trial at the USDA's Agricultural Researc ...