Award Data

DESCRIPTION provided by applicant Therapeutics is focused on the development of adjuvant systems with desired immune activities for targeted indications The Companyandapos s immune stimulatory adjuvant platform builds on combinatorial use of immune agonists with distinct immune targets and mechanisms of action for the generation of therapeutic immune responses Critical to this platform techno ...

ABSTRACT Traditional approaches to drug development for Alzheimer s disease are becoming increasingly expensive and in many cases disappointingly unsuccessful Based on preliminary in vitro and in vivo studies we have identified a novel small molecule methyl dimethyl oxo dihydrobenzo c naphthyridine carboxylate UK that significantly decreases A production and pro in ...

DESCRIPTION provided by applicant Problem Lower gastrointestinal bleeding is a significant medical problem in the United States accounting for more than hospital admissions and tens of billions of dollars of healthcare spending annually It is common for bleeding from a single site to stop and restart multiple times The three modalities now used to diagnose and locate gastrointestina ...

DESCRIPTION provided by applicant There is growing awareness that weakness of muscle is a significant biomedical health issue associated with many different chronic diseases and aging There are a variety of different diseases that affect muscle including muscular dystrophy fibromyalgia cerebral palsy amyotrophic lateral sclerosis and myasthenia gravis each of which carries its own uniqu ...

GTL?s SNS technology aids in the operation of new or existing structural health monitoring (SHM) systems by integrating data and power pathways into the structure. The use of this technology within a composite structure would allow engineers to place sensors from an SHM system directly where they are needed on a structure with instant power. GTL?s SNS technology offers the potential for developers ...

NASA recognizes the importance of conservation, smart utilization and reuse of resources for their deep space missions to address the need for regeneration of air, water and waste with highly reliable systems to reduce mission payload. Additionally, energy for life support and other systems needs to be obtained from renewable energy sources or waste streams. In order to address NASA's requirements ...

DEC-Shield technology offers the means to generate electric power from cosmic radiation sources and fuse dissimilar systems and functionality into a structural component to create a Multi-functional Structure (MFS). DEC-Shield integrated into MFS technology can be used to generate electric power and provide radiation protection in a space vehicle; even maximizing that protection by spreading the ...

Establish a radiation-aware analysis capability in a commercial EDA design flow that will enable first-pass success in radiation-hardened by design (RHBD) for DoD ASICs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications. Layout-aware, calibrated single-event radiation models that captur ...