Award Data

Techulon has developed a platform based on peptide-peptide nucleic acids (PPNAs) molecules that are effective as antimicrobial compounds against multi-drug reisistant pathogens. Techulons targeted approach uses informatic algorithms applied towards an organisms genome to identify targets that will disrupt essential biological functions. The proposed Phase I project will focus on developing a new g ...

The technical objective of this Phase 1 proposal is to develop a non-toxic, multi-component, next generation cryostasis cocktail. We seek to develop a unique, holistic and non-toxic approach to bank human organs for several weeks up to a few months. Our approach is based on using the best strategies employed by freeze-tolerant and hibernating animals in nature and then augmenting them with complem ...

The use of the Walter Reed National Military Medical Center (WRNMMC) can be difficult for patients and visitors to use due to the size and complexity of the facility. The current a kiosk concierge system cannot offer turn-by-turn facility navigation. This proposal seeks to design a combined indoor/outdoor navigation service to aid using and locating services and people in the WRNMMC facility. ...

Traumatic injuries to the head and neck region comprise as much as 30 percent of all combat injuries observed today. These injuries often involve multiple tissues including dermal, muscle, cartilage and bone. This work aims to address this critical need by treating a composite tissue injury model in the ear. We will use an alginate microbead cell delivery system

Major organ injuries such as liver, kidney, heart and lung injuries can lead to high morbidity and mortality in critically ill patients. Advanced noninvasive testing with high sensitivity and specificity is needed to detect specific organ injury particularly at early stages. Current techniques such as PCR, MS, absorption-based assays, ELISA and microfluidic-Luminex, cannot meet such requirements. ...

HemoSonics LLC is developing an easy to use and easy to interpret diagnostic device to rapidly identify diffuse coagulopathies in order to guide proper and evidence-based interventions. The management of diffuse coagulopathies is extremely important in military medicine as these conditions represent a significant source of combat morbidity and mortality. HemoSonics device is based on sonorheome ...

In Topic DTRA143-001, a need has been identified to improve monitoring human presence near containers, stored items, and secured areas in order to monitor activities, particularly in remote locations that are not patrolled all day every day. The use of smart materials to detect human presence by sensing volatile organic compounds emanating from the human body is a major area of interest within the ...

A uniquely qualified team consisting of ETSVP-JV, LLC a small business joint venture, and subcontractor RTI International, are commercializing an innovative reactive nanofiber filtration media for controlling PM2.5 and volatile organic compounds (VOCs). Materials developed for the Department of Defense to protect troops from chemical and biological agents are the foundation for next generation fil ...

Precision Combustion, Inc. (PCI) is developing a regenerable high efficiency filter technology for direct removal of gaseous pollutants such as VOCs and CO2 from indoor air. In addition to controllably improving indoor air quality (IAQ), the direct removal of these pollutants will reduce the requirement for building ventilation with outdoor make-up air currently used to dilute the concentration of ...

This project will result in a high-efficiency, low-cost nanostructure array (nano-array) based NOx aftertreatment devices to meet the need of reducing the NOx emission from the transportation industry and the usage of Pt-group metals (PGM). Synthesized via a low temperature solution process, a nano-array based Lean NOx Trapping (LNT) device will be developed and validated with great advantages ove ...