Award Data

The goal of this workis to establish a radiation-aware capability in a commercial EDA design flow that will enable first-pass success in radiation resiliency for DoD ASIC designs in much the same way that existing EDA design suites ensure first pass functionality and performance success of complex ASICs destined for commercial applications.Such an integrated capability does not presently exist.The ...

Current strategies for the treatment of osteochondral injuries are ineffective and are associated with significant side effects. Microfracture techniques have demonstrated limited efficacy over long periods of time and are less effective for larger osteochondral defects. Osteochondral autograft transplants require harvesting from a donor site, which can lead to donor site morbidity. Further, while ...

Ultrasound is a therapeutic modality which has been used clinically for 60 years, but has been limited in practice by the complexity of the technology. Recent research has allowed for the development of a portable, wearable, long duration, low intensity therapeutic ultrasound system. The system is powered by battery, and can be applied by a user to deliver up

Ultrasound is a therapeutic modality which has been used clinically for 60 years, but has been limited in practice by the complexity of the technology. Recent research has allowed for the development of a portable, wearable, long duration, low intensity therapeutic ultrasound system. The system is powered by battery, and can be applied by a user to deliver up

Parabon NanoLabs (PNL) has designed and demonstrated the feasibility for a new hybrid vaccine nanostructure that is based upon a DNA origami that can include protein antigens or epitopes, immune stimulators, cell targeting ligands and a transfection plasmid.This approach offers the opportunity for crafting molecularly defined vaccine nanostructures that stimulate a specific primary response that i ...

Leveragingour expertise in electro-opto-mechanical device development and system integration (hardware and software) and the Phase-I achievement, Hitron Technologies Inc. (HTI) proposes to develop an autonomous solution tentatively named Tick Collection

HemoSonics LLC is developing an easy to use and easy to interpret diagnostic device to rapidly identify diffuse coagulopathies in order to guide proper and evidence-based interventions. The management of diffuse coagulopathies is extremely important in military medicine as these conditions represent a significant source of combat morbidity and mortality. HemoSonics device is based on sonorheome ...

We have developed a device to control intracranial hemorrhage without a craniotomy.The device stops hemorrhage transcranially.This has been demonstrated in pig cadavers.We have developed a functional prototype and intend to improve and test the device on human cadavers and in vivo in pigs.By the end of the proposed work, we expect to be prepared to submit IDE paperwork with the FDA and engage inve ...

Proposed is the development of an advanced solid state neutron spectrometer (NeuKopis) with directional resolve, building from prototype instruments that have demonstrated the art-of-the-possible. The intrinsic neutron detection efficiency of the refined

Traumatic injuries to the head and neck region comprise as much as 30 percent of all combat injuries observed today. These injuries often involve multiple tissues including dermal, muscle, cartilage and bone. This work aims to address this critical need by treating a composite tissue injury model in the ear. We will use an alginate microbead cell delivery system