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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Achieving Single Nucleotide Resolution to Enable DNA Flossing Through Alpha-Hemolysin

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: NHGRI

    Project Summary Enabling routine DNA sequencing has the potential to improve the understanding of biological processes and relationships as well as aid in medicine forensics and environmental investigations However the potential future benefits of sequencing require a reduction in cost and speed and an improvement in instrumentation accessibility relative to presently commercially available t ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. A Clinical 3D Movement Analysis System for Assessing Lower Extremity Injury Risk and Recovery in Athletes

    SBC: BIONIKS            Topic: NIAMS

    DESCRIPTION provided by applicant The mission of Bioniks is to develop and commercialize accurate low cost movement analysis systems for clinicians ergonomists athletic trainers and other professionals interested in quantifying human movement Our initial focus is on developing computer enhancements for inexpensive D cameras like the Microsoft Kinect These enhancements surpass the accura ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. A closed-loop assessment and treatment platform for mood disorders

    SBC: POSIT SCIENCE CORP            Topic: 104

    PROJECT SUMMARY The goal of the current project is to elaborate upon reconstruct and advance to pivotal trial readiness a multimodal closed loop assessment to treatment mobile application for individuals with mood disorders Major Depressive Disorder MDD is a recurrent and disabling condition and a leading cause of global disease burden Nearly half of the patients fail to respond to psycho ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. A Clothing-Adhered Wearable to Monitor Biomarkers of Cognitive/Emotional State and Deliver Just-in-Time Behavioral Interventions

    SBC: Spire, Inc.            Topic: NIDA

    PROJECT SUMMARY Recovery from substance use disorders (SUDs) is greatly impacted by the cognitive and emotional state of the individual, and learning new thought and behavioral patterns can facilitate successful treatment and recovery. Specifically, fluctuations in stress or anxiety can trigger lapses to drug use. Even when actual use is avoided, stress-induced craving is likely to be distracting ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. A Comprehensive Fall Prevention System for Memory Care: Final Feasibility and Randomized Controlled Study

    SBC: SAFELYYOU INC.            Topic: NIA

    Abstract In the USAlzheimer s diseaseADis the single most expensive diseasethe only disease in the top six for which the number of deaths is increasingThe greatest cost contributors are frequent hospitalizationswhere falls are the largest culpritand frequent need for assistance with the activities of daily livingFall safety systems show the potential to reduce costs and increase quality of care by ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. A computational approach to early sepsis detection

    SBC: Dascena, Inc.            Topic: NCATS

    Abstract SignificanceIn this SBIR projectwe propose to improve the performance of InSighta machine learningbased sepsis screening systemin situations of limited training data from the target clinical siteThe proposed work will make possible prospective clinical deployments to sites which are smaller or lack clinical data repositoriesby significantly reducing the amount of training data necessary d ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. A Customizable Real-Time Biosensor for Continuous Monitoring of Water Contaminants

    SBC: QUANTITATIVE BIOSCIENCES, INC.            Topic: NIEHS

    Ensuring access to clean water for generations to come will involve developing novel approaches to determining the safety and composition of potable water that are practical and affordableArsenicmercuryand cadmium are three of the top priorities among hazardous substances commonly found at Superfund sitesas they are linked to health problems in people exposed to them in drinking wateryet the curre ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Adaptable and Automated Large-Scale Manufacturing of iPSC-Derived Cell Products

    SBC: ALLELE BIOTECHNOLOGY AND PHARMACEUTICALS            Topic: NHLBI

    Summary Statement and Abstract Stem cell technology is revolutionizing regenerative medicine and cell based therapies One of the promising applications of this technology is stem cell derived platelet Platelets are in high demand for a number of medical treatments but general or matching sources may be limited for various reasons A continuous donor independent and universally compatible suppl ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Adjuvant Development for a Thermostable Respiratory Influenza Vaccine

    SBC: UNIVERSAL STABILIZATION TECHNOLOGIES, INC.            Topic: NIAID

    The objective of the proposed project is evaluation of two novel non aluminum vaccine adjuvantsCpG ODN and AdVaxinulin polysaccharidewith intranasal delivery of thermostable live attenuated influenza vaccineLAIVand irradiation inactivation inactivated influenza vaccineIr IIVpowdersThe proposal aims to formulate thermostable vaccines in the dry powder format using patented Preservation by Vaporizat ...

    SBIR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Administrative Supplement to restore fee funds

    SBC: AMERICAN LIFE SCIENCE PHARMACEUTICALS, INC.            Topic: NINDS

    Project Summary Traumatic brain injuryTBIcauses detrimental behavioral dysfunctions and brain neurodegeneration butunfortunatelythere currently is no effective pharmaceutical TBI treatmentThe underlying PhaseSTTR grant is to develop a new class of TBI drugs that inhibit the protease cathepsin BGenetically deleting the cathepsin B gene in mice results in substantial behavioral and pathology improve ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
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