Award Data

Industrial Microbes is developing a green fermentation platform to replace carbon-emitting petrochemical production with newer methods that build chemicals out of methane and carbon dioxide.Chemical production is a major source of carbon pollution, responsible for 18% of direct industrialemissions. Our innovation is an engineered microbe that can consume carbon dioxide and methane and produce a ch ...

Over 50 million Indian households cook on a bio-mass fire and have unreliable or no electricity but are anxious to purchase an affordable power stove which will provide on-demand power and lighting to their homes. Annually, projected sales of the power stove could save sixteen million trees, reduce cooking fire particulates by 90%, reduce the two million premature deaths caused from indoor air pol ...

Discharge of nutrients (e.g. phosphorus and ammonia) to surface waters can cause eutrophication and the formation of toxic algal blooms, threatening human health and the environment. However, current phosphorus treatment technologies such as chemical precipitation and conventional biological systems can be costly and ineffective to reliably achieve impending effluent regulatory limits of

TIAX has developed a technology that meets the EPA' s need for decontamination of biological material in railway and subway cars. It provides simultaneous encapsulation and killing of biological contaminants with the added capability for decontamination of chemical and radiological hazards. Current technologies are manpower intensive involving separate steps for site preparation; decontamination; ...

San Diego Composites, Inc. (SDC) is developing the Reinforced Additively Manufactured Compression Assisted Molding (RAMCAM) pod to produce on-demand, corrosion resistant, aluminum and stainless steel equivalent parts in less than three days. RAMCAM combines the advantageous 2 day lead time of custom parts produced by 3D printing with the 1 day forging of structural parts via composite compression ...

The modern warfighter faces the constant threat of endemic infections, multi-drug resistant bacteria and Biological Warfare Agents. In order to provide accurate front-line treatment that will curtail the overuse of antibiotics, a rapid and robust molecula

The focus of this SBIR proposal is to demonstrate rapid, multiplexed detection of acute bacterial and viral pathogens of global importance on asingle test platform. Daktaris microfluidic immunoassay platform, under development since 2009 for HIV and hepatitis C (HCV) applications, iscapable of femtomolar detection of bacterial and viral antigens consistent with needs for infectious disease diagnos ...

In this proposal, we aim to validate the human gut microbiome and arid soil as a source of antibiotic natural products (NPs ) by using ametagenomic NP discovery platform developed at Radiant Genomics. Recent studies suggest that the genomes of uncultivated microorganisms,like their cultivated counterparts, encode an enormous number of NPs. Gaining systematic access to NPs using standard, cultivati ...

Environmental DNA from three extreme samples will be isolated, cloned into a fosmid library (5760 clones) for sequencing. The sequencing datawill cover ~ 240 Megabases and will be assembled into contigs long enough (~ 40 Kilobases) to represent potential biosynthetic gene clusters(BGCs). This data will be compared to BGC databases looking for homology to antibiotic targets of DoD interest and with ...

Physical Sciences, Inc. (PSI) proposes to develop a PCS-Enabled Smart Device Toolkit that will reduce the cost of training personnel and the time required to detect, identify, and localize a radiological source. The ability to simulate the response of a radiation detector to a virtual source for training purposes will be developed. This simulation will be based on a data fusion algorithm to accura ...