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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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AAV-AIBP Therapy for Alzheimer's Disease
SBC: RAFT PHARMACEUTICALS LLC Topic: NIAPROJECT SUMMARY Therapy for Alzheimer’s disease and related dementias (AD/ADRD), slow-progressing neurodegenerative diseases, remains elusive. Therapeutic approaches focusing on beta amyloid (Aβ) removal from the brain or on targeting genes for which strong associations between their polymorphism and AD/ADRD are established, have had a mixed record of success. We propose a novel strategy to rev ...
STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health -
A Cancer Vaccine for Ovarian and Breast Cancer
SBC: EPIMMUNE, INC. Topic: N/ADESCRIPTION (provided by applicant): The overall objective of this STTR program is to develop an effective cancer vaccine based on class II T cell epitopes derived from four tumor-associated antigens (TAAs) that are commonly over-expressed in ovary-and breast-derived tumors. The role of CD4+ T cell in eliciting an anti-tumor response is critical. The development of tumor specific CTL and the ge ...
STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health -
Accessible and Robust High-Throughput Western Blotting for Small Sample Sizes
SBC: BLOTTING INNOVATIONS, LLC Topic: 400PROJECT SUMMARY The goal of this Phase I STTR is for Blotting Innovations, LLC to establish feasibility of a commercializable mesowestern—a high-throughput, affordable western blotting technique that we recently developed. Western blotting is a technique for molecular-weight-resolved analysis of proteins and their post-translational modifications that is practiced today almost identically to whe ...
STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health -
Acid Ceramidase, Target for Cancer
SBC: Sphingogene, Inc Topic: N/ADESCRIPTION (provided by applicant): Acid ceramidase (AC) has been implicated as a novel target for cancer therapy because of its pivotal role in regulating interconversion of three key bioactive lipids; ceramide (Cer), sphingosine (Sph) and Sphingosine-1-Phosphate (S1P). It is well known that Cer functions predominantly as a tumor suppressor lipid and mediator of apoptosis following chemo and rad ...
STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
A Clinical 3D Movement Analysis System for Assessing Lower Extremity Injury Risk and Recovery in Athletes
SBC: BIONIKS Topic: NIAMSDESCRIPTION provided by applicant The mission of Bioniks is to develop and commercialize accurate low cost movement analysis systems for clinicians ergonomists athletic trainers and other professionals interested in quantifying human movement Our initial focus is on developing computer enhancements for inexpensive D cameras like the Microsoft Kinect These enhancements surpass the accura ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Acne Vaccines Targeting a Surface Sialidase and a Secreted CAMP Factor Toxin
SBC: VAXIN INC. Topic: N/ADESCRIPTION (provided by applicant): Propionibacterium acnes (P. acnes) is most notably recognized for its role in acne vulgaris, the most common skin disease, affecting 85-100% of the population at some point in their lives. Current treatments for vulgari s acne using isotretinoin (13-cis-retinoic acid) or antibiotics can have many undesirable effects, including depression, teratogenicity, hormon ...
STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health -
Acoustic Device for Spine Surgery
SBC: SONOSCREW, INC. Topic: N/ADESCRIPTION (provided by applicant): An Acoustic Device for Preventing Spine Surgery Complications A specific and immediate concern arises in spine surgery, where an inserted instrument can damage the structures around the spine. For example, a device can be advanced too far into the vertebral body, and can cause damage to the nearby spinal cord and spinal nerve roots. These complications occur d ...
STTR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health -
Acute-infarct selective cardiac MRI contrast agent
SBC: ELGAVISH PARAMAGNETICS, INC. Topic: N/ADESCRIPTION (provided by applicant): Reliable diagnostic differentiation between acute and chronic myocardial infarcts would be of great benefit for cardiac surgeons and interventional cardiologists. Such differentiation could be used to make decisions about which vessels and in what order would be reopened or bypassed. MRI is an intrinsically noninvasive diagnostic tool and the Delayed Enhancemen ...
STTR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health -
A decellularized porcine placenta matrix hydrogel for management of radiation-induced proctitis
SBC: Briopryme Biologics, Inc. Topic: 102PROJECT SUMMARY Radiation therapy is a widely used treatment modality for pelvic malignancies such as prostate and cervical cancer; however, the high doses needed to confer therapeutic benefit often inflict significant damage on the normal issue in and surrounding the radiation field. The most frequent complication of pelvic radiation is proctitis, which nearly all patients experience acutely and ...
STTR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health -
Adenovirus vectored vaccines for Alzheimer's disease
SBC: VAXIN INC. Topic: N/ADESCRIPTION (provided by applicant): Alzheimer disease (AD) is the most common neurodegenerative disease in the elderly. To date, no satisfactory treatment is available for AD. One of the pathological hallmarks of AD is deposits of amyloid protein (Aa) in neuritic plaques and cerebral vessels. Increasing lines of evidence support the notion that Aa and its precursor (APP) play pathogenetic roles i ...
STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health