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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. An eHealth solution for posttraumatic stress and pain screening integrated in pediatric injury care

    SBC: Radiant Creative Group, LLC            Topic: NICHD

    DESCRIPTION provided by applicant Each year million US children are injured affecting the child his her family and society which often bears the cost Among school age children age to injuries lead to million emergency department ED visits and hospital admissions annually resulting in $ billion in medical costs and $ billion more in work loss costs Approxima ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. An electrode-based resistivity tool for fracture diagnostics in steel-cased wellbores

    SBC: E-Spectrum Technologies, Inc.            Topic: 19

    Hydraulic fractures must be contained within the target formation so that they do not contact and potentially contaminate sources of drinking water. To mitigate this risk, research is needed to develop technologies that will advance our ability to diagnose, quantify, and map hydraulic fractures and thus help mitigate the danger that hydraulic fracturing results in the contamination of subsurface p ...

    STTR Phase I 2016 Department of Energy
  3. Aptamers and BSI for Sub-Microliter Analysis of Pharmaceuticals in Neonatal Urine

    SBC: Base Pair Biotechnologies, Inc.            Topic: NICHD

    DESCRIPTION provided by applicant Neonatal and pediatric intensive care still involves performing painful needle punctures to obtain blood samples for routine clinical monitoring Pain management in the neonatal setting is often achieved by long term continuous intravenous infusion of morphine or related compounds It has become increasingly clear however that long term use of opioid compound ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. ARCHER- An Extremely Fast Medical Radiation Dose Computing Software

    SBC: VIRTUAL PHANTOMS INC            Topic: NIBIB

    DESCRIPTION provided by applicant The goal of this project is to develop a commercial software package for rapid Monte Carlo based dose computation in imaging and radiation therapy The product takes advantage of a desktop parallel computer equipped with emerging hardware originally developed gaming and high performance computing The project is motivated by the fact that the market is ripe for ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. A sample-to-answer diagnostic cartridge that identifies influenza using a glucometer

    SBC: Paratus Diagnostics            Topic: NIAID

    Project Summary Abstract Seasonal influenza has an annual global incidence of up to in adults and up to in children About to million infections result in severe disease while somewhere between a quarter and a half million cases are fatal Antiviral drugs can lessen the severity and reduce mortality when administered within h of onset of symptoms Hence sensitive and specific poin ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. A simple and effective diagnostic test for gastrointestinal bleeding to improve patient outcomes

    SBC: CUMBERLAND PHARMACEUTICALS INC.            Topic: 300

    DESCRIPTION provided by applicant Problem Lower gastrointestinal bleeding is a significant medical problem in the United States accounting for more than hospital admissions and tens of billions of dollars of healthcare spending annually It is common for bleeding from a single site to stop and restart multiple times The three modalities now used to diagnose and locate gastrointestina ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. A small molecule integrin activator to enhance cord blood transplant

    SBC: 7 Hills Pharma LLC            Topic: NHLBI

    DESCRIPTION provided by applicant This proposal is in response to PA the parent announcement for STTR R grant applications Hematopoietic stem cell transplantation has become a preferred treatment for hematological malignancies and certain genetic disorders The use of umbilical cord blood cells as a source of hematopoietic stem cells for bone marrow transplantation has increased st ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Developing a novel adjuvant system for therapeutic vaccines against lung cancer

    SBC: FasCure Therapeutics LLC            Topic: 102

    DESCRIPTION provided by applicant Therapeutics is focused on the development of adjuvant systems with desired immune activities for targeted indications The Companyandapos s immune stimulatory adjuvant platform builds on combinatorial use of immune agonists with distinct immune targets and mechanisms of action for the generation of therapeutic immune responses Critical to this platform techno ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Development of a Polymeric Percutaneous Pulmonary Valve for Use in Young Children

    SBC: Polyvascular Corp            Topic: NHLBI

    DESCRIPTION provided by applicant Congenital heart defects CHD represent the most common type of birth defect and are a leading cause of childhood deaths in the developed world Many forms of CHD require pulmonary valve PV replacement surgery which is typically performed with biologic valves such as human cadaveric donor valves which are in short supply Additionally such biologically ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a small molecule activator of integrin cell adhesion to enhance therapeutic responses to checkpoint blockade in cancer

    SBC: 7 Hills Pharma LLC            Topic: 102

    DESCRIPTION provided by applicant Recent FDA approvals of ipilimumab nivolumab and pembrolizumab which target checkpoint receptors cytotoxic T lymphocyte associated antigen CTLA and programmed death PD have ushered in a new era of cancer immunotherapy in metastatic melanoma Despite unprecedented overall survival benefits with combination therapy the incidence of complete respo ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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