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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Validation of a salivary miRNA diagnostic test for autism spectrum disorder
SBC: Quadrant Biosciences Inc. Topic: 105Project Summary Abstract Autism spectrum disorder ASD is a continuum of neurodevelopmental characteristics that includes deficits in communication and social interaction as well as restrictive repetitive interests and behaviors ASD is an increasing public health concern with about in American children diagnosed with ASD in a fold increase in prevalence over the past years T ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Therapy for drug resistant influenza strains by nucleic acid targeting of respiratory airways
SBC: Abcombi Biosciences Inc Topic: NIAIDPROJECT SUMMARY Antiviral drugs are a crucial countermeasure for influenza A virus IAV particularly in circumstances of increased IAV incidence or if a vaccine is unavailable e g virulent H N IAV However the emergence of IAV strains that are resistant to current antivirals H N underscores the need for new treatment strategies particularly those that modify the host response IAVs ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
TheraBracelet: The first and only wearable to instantly improve stroke hand function
SBC: TheraBracelet, Inc. Topic: NICHDProject SummaryPost stroke hand impairment is highly prevalent and severely restricts functional ability and independenceIn facteveryseconds a new stroke occursand stroke is recognized as the leading cause of long term disabilityYetthere is no assistive device to help hand function at homeevery dayduring activities of daily livingExisting devices such as hand opening orthoses are expensivee gMyomo ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
The Effects of an Oral Nitric Oxide Lozenge on Peripheral Artery Disease
SBC: Neogenis Laboratories, Inc. Topic: 213Abstract Peripheral artery disease PAD is a common circulatory problem in which narrowed arteries reduce blood flow to your limbs thereby restricting blood flow During exercise or simply walking there is not sufficient blood flow to keep up with the metabolic demand This causes symptoms most notably leg pain when walking intermittent claudication PAD is also likely to be a sign of more w ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Targeting Synaptotagmin to Prevent Airway Mucus Obstruction
SBC: Exotect, LLC Topic: NHLBIPROJECT SUMMARY Mucus dysfunction underlies the pathophysiology of a number of common respiratory diseases including asthma cystic fibrosis and chronic obstructive pulmonary disease COPD Asthma alone impacts of the US population resulting in considerable cost morbidity and occasional mortality caused by mucus hypersecretion Recently it was discovered that Synaptotagmin Syt regul ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Target Identification for Novel Small Molecule Therapeutic for Alzheimer's disease
SBC: CoPlex Therapeutics, LLC Topic: NIAABSTRACT Traditional approaches to drug development for Alzheimer s disease are becoming increasingly expensive and in many cases disappointingly unsuccessful Based on preliminary in vitro and in vivo studies we have identified a novel small molecule methyl dimethyl oxo dihydrobenzo c naphthyridine carboxylate UK that significantly decreases A production and pro in ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Targeted Epigenetic Therapy for Triple-Negative Breast Cancer
SBC: PARKSIDE SCIENTIFIC INC. Topic: 102DESCRIPTIONprovided by applicantTriple negative breast cancerTNBCis one of the most aggressive forms of human cancerand currently has no targeted therapyChemotherapy is the only available treatment for TNBC patientsbut is deleterious and not effective once tumor spreadsTNBC represents a major unmet medical needaboutof breast cancer incidenceswomen worldwide inare TNBCTNBC disproportionally affects ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Structure based optimization of a novel pharmacological chaperone therapy for MPSIIIC
SBC: Phoenix Nest Inc. Topic: NICHDPROJECT SUMMARY Lysosomal storage diseases LSD are rare inherited metabolic disorders caused by defects in the cellular catabolic system Mucopolysaccharidosis Type IIIC MPS IIIC or Sanfilippo disease type C is one such LSD that is caused by deficiency of the enzyme heparan sulfate acetyl CoA glucosaminide N acetyltransferase HGSNAT essential for degradation of heparan sulfate a repeati ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
STAT Inhibitors for Asthma Therapy
SBC: Atrapos Therapeutics, LLC Topic: NIAIDAsthma a chronic disease of the lungs that affects adults and children of all ages has markedly increased in incidence prevalence and severity over the past several decades with a prevalence of in the U S The current standard of care for asthma consists of the combination of long acting beta adrenergic receptor agonists which relieve airway constriction and glucocorticosteroids which ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Smaller, Brighter Probes for Correlative Super-resolution and Electron Microscopy
SBC: NANOPROBES INC Topic: NIGMSDESCRIPTION provided by applicant We propose new probes for correlative super resolution fluorescence and electron microscopy that use biorthogonal reactions Click SNAP and HALO tags to label targets in living cells To minimize quenching of the fluorophores by the gold particles the small Undecagold gold atoms gold cluster label will be used this has minimal absorption at wavelengt ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health