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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Bio-manufacturing process for fabrication of 3D scaffolds with cell culture der

    SBC: 3D Biotek, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this research is to develop novel 3D biodegradable porous polymer scaffolds with biomimetic extracellular matrix (ECM) coating for tissue engineering application. This SBIR Phase I proposal is to demonstrate the scaffold manufacturing feasibility by using a proprietary precision extruding deposition technique to fabricate porous 3D tissue scaff ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  2. Abuse Deterrent Transdermal Drug Delivery System for Fentanyl

    SBC: BIONEX PHARMACEUTICALS LLC            Topic: NIDA

    Pain is the single greatest cause of disability and its management remains one of medicine s foremost challenges Potent opiates can effectively reduce the severity of pain thereby diminishing patient suffering Unfortunately chronic use of these drugs can be harmful to patients whether by inadvertent overdosing unintentional addiction or abuse resulting from dependency on the euphoric effec ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Accelerated Repair of Vascular Injury in Diabetes by TGF-beta Modified Stem Cells

    SBC: BETASTEM THERAPUETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Accelerated Repair of Vascular Injury in Diabetes by TGF-beta Modified Stem Cells Abstract: Stem cells of hematopoietic origin (HSC) have been described that have the potential to repair vascular injury (CD34+ stem cells). We have recently demonstrated that a blockade of endogenous transforming growth factor-beta type 1 (TGF-21) in murine and human hematopoieti ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  4. Achieving Single Nucleotide Resolution to Enable DNA Flossing Through Alpha-Hemolysin

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: NHGRI

    Project Summary Enabling routine DNA sequencing has the potential to improve the understanding of biological processes and relationships as well as aid in medicine forensics and environmental investigations However the potential future benefits of sequencing require a reduction in cost and speed and an improvement in instrumentation accessibility relative to presently commercially available t ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. A Clinical 3D Movement Analysis System for Assessing Lower Extremity Injury Risk and Recovery in Athletes

    SBC: BIONIKS            Topic: NIAMS

    DESCRIPTION provided by applicant The mission of Bioniks is to develop and commercialize accurate low cost movement analysis systems for clinicians ergonomists athletic trainers and other professionals interested in quantifying human movement Our initial focus is on developing computer enhancements for inexpensive D cameras like the Microsoft Kinect These enhancements surpass the accura ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. A Clinical High Resolution Imaging System (CHRIS)

    SBC: LYNCEAN TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop an innovative prototype imaging system which combines the unique properties of the Compact Light Source (a new x-ray source developed with NIGMS SBIR funding) with a new imaging method called Differential Phase Contrast Imaging. This Clinical High Resolution Imaging System (CHRIS) will yield x-ray images which can distinguish subtle variat ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  7. A closed-loop assessment and treatment platform for mood disorders

    SBC: POSIT SCIENCE CORP            Topic: 104

    PROJECT SUMMARY The goal of the current project is to elaborate upon reconstruct and advance to pivotal trial readiness a multimodal closed loop assessment to treatment mobile application for individuals with mood disorders Major Depressive Disorder MDD is a recurrent and disabling condition and a leading cause of global disease burden Nearly half of the patients fail to respond to psycho ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. A Combination Endovascular Device Therapeutic Hypothermia with Stentriever Devices

    SBC: Tom L Merrill            Topic: 106

    Project Summary Stroke is the th leading cause of death and number one cause of adult disability in the United States The primary goal of ischemic stroke treatment is quickly restoring blood perfusion However studies have shown that this return of blood flow while necessary can also cause damage to local tissue Hypothermia has been shown to decrease this reperfusion injury The overall go ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Active Distributed Electrode Array Network for Electrical Stimulation Therapy

    SBC: CUSTOMKYNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Transcutaneous electrical stimulation applications involving high numbers of stimulated muscles have been an area of growing interest in recent years. customKYnetics has been approached in recent months by research groups and stimulation application developers requesting high channel count stimulation devices for use in their spinal cord injury rehabilitation ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
  10. Acute Ischemia Monitor Utilizing Subcutaneous Electrodes

    SBC: ANGEL MEDICAL SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We will develop a chronically implanted heart monitor that detects acute ischemia by analyzing electrocardiographic (ECG) waveforms recorded by subcutaneous electrodes. The two specific aims of this Phase I research are: (1) to further develop our ischemia detection algorithm by refining heart-rate based adjustment of ECG feature thresholds and optimizing tempo ...

    SBIR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health
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