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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Advanced Image Analysis Tools for Diabetic Retinopathy Telemedicine Application

    SBC: EYENUK, INC.            Topic: NEI

    Abstract In this Commercialization Readiness Pilot CRP Program application we propose to commercialize and bring to market EyeArt a fully automated high throughput retinal image analysis based diabetic retinopathy DR screening tool which has been developed and already validated in bench tests on very large real world data by developing and executing a market access plan conducting a pi ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Near patient molecular diagnostics test for infections

    SBC: GeneFluidics, Inc.            Topic: R

    ABSTRACT Currently there are no FDA cleared molecular based tests for urinary tract infection UTI pathogen identification and antimicrobial susceptibility testing to replace the andapos gold standardandapos of dipstick urinalysis and urine culturing All pathogen identification tests still rely on clinical isolates from urine cultures largely unchanged from Kochandapos s postulates developed ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Mobile Application to Deliver Personalized Nutrition for the Prevention of Alzheimer s Disease

    SBC: GENBEN LIFESCIENCES CORPORATION            Topic: NIA

    Genben Lifesciences dba GB HealthWatch is a digital health and nutritional genomics company Our mission is to help fight common diet and lifestyle related chronic diseases with precision nutrition and advanced mobile technologies Our company developed the HealthWatch mobile app for tracking dietary intake physical activity and health related symptoms This mobile app has received excell ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Fully automated enzymatic radiolabeling of biomolecules

    SBC: Sofie Biosciences, Inc.            Topic: NIBIB

    PROJECT SUMMARY ABSTRACT Despite their inherent potential the use of F protein radiotracers in both preclinical and clinical settings is hampered by a lack of robust radiolabeling techniques We aim to address this by developing a fully automated radiolabeling methodology that is site specific occurs rapidly under mild aqueous conditions and requires only small amounts of precursor peptide ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Biofueled Thermoelectric Cookstove

    SBC: HI-Z TECHNOLOGY, INC.            Topic: 15NCER02

    Over 50 million Indian households cook on a bio-mass fire and have unreliable or no electricity but are anxious to purchase an affordable power stove which will provide on-demand power and lighting to their homes. Annually, projected sales of the power stove could save sixteen million trees, reduce cooking fire particulates by 90%, reduce the two million premature deaths caused from indoor air pol ...

    SBIR Phase I 2016 Environmental Protection Agency
  6. High-Efficiency Nutrient Removal and Recovery for Achieving Low Regulatory Limits

    SBC: MICROVI BIOTECH, INC.            Topic: 15NCER05

    Discharge of nutrients (e.g. phosphorus and ammonia) to surface waters can cause eutrophication and the formation of toxic algal blooms, threatening human health and the environment. However, current phosphorus treatment technologies such as chemical precipitation and conventional biological systems can be costly and ineffective to reliably achieve impending effluent regulatory limits of

    SBIR Phase I 2016 Environmental Protection Agency
  7. Antimicrobial Endotracheal Tube to Combat Biofilm

    SBC: ALLVIVO VASCULAR, INC.            Topic: NHLBI

    ABSTRACT Ventilator associated pneumonia VAP is one of the most costly and deadly nosocomial infections Over cases of VAP occur per year resulting in over deaths and a cumulative annual cost to the US Healthcare system over Billion Endotracheal tubes ETT are inserted into the trachea to allow mechanical ventilation They are a critical part of the ventilator circuit but also ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Identification of RORg drug candidates for the treatment of NASH

    SBC: VISIONARY PHARMACEUTICALS, INC.            Topic: 300

    ABSTRACT Significance An epidemic proportion of Americans approximately million suffer from obesity and nonalcoholic fatty liver disease a spectrum of progressive liver disease that include steatosis non alcoholic steatohepatitis NASH fibrosis and eventually cirrhosis and hepatocellular carcinoma HCC There is no standard of care pharmacotherapy for NASH Therefore new thera ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Small molecule activators of alpha crystallin for non surgical treatment of cataracts

    SBC: Plex Pharmaceuticals, Inc.            Topic: N

    Project Summary Cataract the clouding of the eye lens is responsible for of world blindness According to World Health Organization nearly million people are bilaterally blind from cataract in the world Cataract is easily treated by surgery and is considered as one of the most cost effective interventions Although cataract surgery is generally considered to be safe there are significan ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Multivalent Anti VEGF Conjugates for Sustained Treatment of Diabetic Retinopathy

    SBC: Valitor, Inc.            Topic: N

    Project Summary In approximately million Americans with diabetes were living with the accompanying condition diabetic retinopathy which is the largest cause of blindness among working age individuals in the United States During the progression of DR ischemic neuronal cells in the retina begin to express vascular endothelial growth factor A VEGF A leading to macular edema and retinal ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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