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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Advanced Image Analysis Tools for Diabetic Retinopathy Telemedicine Application

    SBC: EYENUK, INC.            Topic: NEI

    Abstract In this Commercialization Readiness Pilot CRP Program application we propose to commercialize and bring to market EyeArt a fully automated high throughput retinal image analysis based diabetic retinopathy DR screening tool which has been developed and already validated in bench tests on very large real world data by developing and executing a market access plan conducting a pi ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. An epitope focused nanoparticle vaccine for MRSA and biodefense

    SBC: VLP BIOTECH, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Overall Staphylococcus aureus is a gram positive bacteria which possesses a multitude of virulence factors It is a frequent and severe pathogen in hospitals and of increasing concern in the community where it results in severe skin infections pneumonia bacterial endocarditis and sepsis A significant proportion of these infections are the result of methici ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. A Novel Recombinant Protein as an Effective Therapy for Acute Kidney Injury

    SBC: THERASOURCE, LLC            Topic: 400

    PROJECT DESCRIPTION The primary objective of this project is to demonstrate the feasibility of developing recombinant human milk fat globule epidermal growth factor factor rhMFG E as a novel and effective therapeutic for patients with acute kidney injury AKI associated with ischemia due to low renal perfusion AKI is a major cause of prolonged hospitalization and increased mortality Ische ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel TLR Agonist Based Adjuvant for Poliovirus Vaccine

    SBC: BUFFALO BIOLABS, LLC            Topic: NIAID

    PROJECT SUMMARY ABSTRACT Antiviral vaccines remain the largest segment of the rapidly growing global vaccine market Despite near complete eradication of poliovirus through vaccination efforts continued need for inactivated polio vaccine IPV is projected to reach million doses per year worldwide Among major obstacles to widespread use of the current IPV formulation are its high cost and in ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Antimicrobial Endotracheal Tube to Combat Biofilm

    SBC: ALLVIVO VASCULAR, INC.            Topic: NHLBI

    ABSTRACT Ventilator associated pneumonia VAP is one of the most costly and deadly nosocomial infections Over cases of VAP occur per year resulting in over deaths and a cumulative annual cost to the US Healthcare system over Billion Endotracheal tubes ETT are inserted into the trachea to allow mechanical ventilation They are a critical part of the ventilator circuit but also ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. A Platform Approach for the Electrical Detection of Protein Biomarkers using a Nanopore Device

    SBC: ONTERA INC.            Topic: NIBIB

    DESCRIPTION provided by applicant The long term objective of the proposed research is to create a fully automated hand held platform for nanopore based biomarker detection and quantitation Our single molecule assay currently has a time to results of minutes or less achieves pM sensitivity without optimization and costs $ materials and labor per test by using a disposable test strip mod ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Assessing psychosis related deficits based on gaze behavior

    SBC: Eye-Predict            Topic: 101

    DESCRIPTION provided by applicant Assessing psychosis related deficits based on gaze behavior Existing tests of psychotic disorders are either functionally informative or biologically valid but rarely both The ultimate project goal is to improve behavioral health and reduce societal costs by providing a battery of user friendly tests that offer functional relevance couple with biological vali ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. Automated Basic Reading Assessment

    SBC: Analytic Measures Incorporated            Topic: 1

    This project team will develop and test a prototype of Moby.Read, a stand-alone app for handheld devices or tablets. Using Moby.Read, grade school students will read a passage out loud and the speech-recognition software will generate an assessment of oral-reading fluency in real-time. The app is intended to replace face-to-face oral reading assessments done by teachers in order to save teachers t ...

    SBIR Phase I 2016 Department of Education
  9. Biofueled Thermoelectric Cookstove

    SBC: HI-Z TECHNOLOGY, INC.            Topic: 15NCER02

    Over 50 million Indian households cook on a bio-mass fire and have unreliable or no electricity but are anxious to purchase an affordable power stove which will provide on-demand power and lighting to their homes. Annually, projected sales of the power stove could save sixteen million trees, reduce cooking fire particulates by 90%, reduce the two million premature deaths caused from indoor air pol ...

    SBIR Phase I 2016 Environmental Protection Agency
  10. Chikungunya Recombinant Subunit Vaccine

    SBC: Hawaii Biotech, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Chikungunya virus CHIKV is an alphavirus classified as a category C priority pathogen that causes fever rash and arthralgia in humans In the past decade CHIKV outbreaks have spread beyond the endemic regions of Africa and Asia first to the islands in the Indian Ocean and most recently to the Americas The World Health Organization has reported that as ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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