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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of a Biochemical Diagnosis for Creutzfeldt Jakob disease

    SBC: Amprion, Inc.            Topic: 101

    ABSTRACT Human prion diseases are infectious and invariably fatal neurodegenerative diseases including sporadic Creutzfeldt Jakob disease sCJD the most common form and variant CJD vCJD which is associated to consumption of cattle meat infected by bovine spongiform encephalopathy Currently there is not sensitive objective and non invasive biochemical diagnosis for these diseases and even ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Near patient molecular diagnostics test for infections

    SBC: GeneFluidics, Inc.            Topic: R

    ABSTRACT Currently there are no FDA cleared molecular based tests for urinary tract infection UTI pathogen identification and antimicrobial susceptibility testing to replace the andapos gold standardandapos of dipstick urinalysis and urine culturing All pathogen identification tests still rely on clinical isolates from urine cultures largely unchanged from Kochandapos s postulates developed ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. The Allogeneic Heart Stem Cell Trial in Hypoplastic Left Heart Syndrome Patients

    SBC: CAPRICOR, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant One of the most complex forms of congenital heart disease hypoplastic left heart syndrome HLHS affects an average of in every newborns with a mortality rate of up to percent during the first year of life The overall goal f our research is to develop safe and effective ways to improve short term and long term survival rates in babies born with HL ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Advanced Image Analysis Tools for Diabetic Retinopathy Telemedicine Application

    SBC: EYENUK, INC.            Topic: NEI

    Abstract In this Commercialization Readiness Pilot CRP Program application we propose to commercialize and bring to market EyeArt a fully automated high throughput retinal image analysis based diabetic retinopathy DR screening tool which has been developed and already validated in bench tests on very large real world data by developing and executing a market access plan conducting a pi ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Lab-on-a-Chip-Based System for Detection and Monitoring of Oral Cancer in Dental Settings

    SBC: SensoDX II, LLC            Topic: NIDCR

    DESCRIPTION provided by applicant Cancers of the oral cavity and pharynx are among the most serious cancers with approximately incidents globally In the US the year survival rate is approximately among the lowest for all forms of cancer Yet when diagnosed in the early stages with confinement to the primary site the rate increases dramatically to about Further cancers of the oral cavity are among t ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. IGF OT IGF DESIGNING METHODOLOGICALLY RIGOROUS ANIMAL STUDIES XDA EXPERIMENTAL DESIGN ASSISTANT N DA AUGUST AUGUST

    SBC: TIETRONIX SOFTWARE INC            Topic: NIDA

    Under this Small Business Innovation Research SBIR Phase II project Research Topic for "XDA eXperimental Design Assistant" the Contractor shall complete development of a platform to assist addiction and other life science investigators in designing in vivo animal experiments

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Whole Brain Nanoscale Preservation Imaging

    SBC: Nectome Inc.            Topic: 101

    Abstract Summary Nectome will create technologies to enable whole brain nanoscale preservation and imaging a vital step towards a deep understanding of the mind and of the brainandapos s diseases Current brain processing technologies compromise between whole brain applicability or nanoscale resolution our technologies will achieve both si multaneously Similar to the way that next generation ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. PEBank: A database for protein engineering data

    SBC: PROTABIT, LLC            Topic: 400

    DESCRIPTION provided by applicant Engineered proteins such as therapeutic antibodies specialized enzymes for drug manufacturing and proteins used to identify new small molecule drugs are making significant contributions to improve health care Protein therapeutics alone represent a $ billion market that is rapidly growing and has broad applications in the treatment of cancer metabolic diseases and ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Commercial development of microwire bundle technology for massively parallel neural recording

    SBC: Paradromics, Inc.            Topic: 101

    DESCRIPTION provided by applicant This proposal describes a novel approach for recording from tens of thousands of neurons simultaneously using bundles of microwires that are each smaller than a human hair To accomplish this thousands of microwires are bundled together with one end being inserted into the brain and the other being bonded to a high speed image sensor chip that reads out the v ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. VALIDATION OF AN IN VITRO ASSAY FOR ANDROGENIC ACTIVITY

    SBC: CERTICHEM INC            Topic: NIEHS

    DESCRIPTION provided by applicant Recent scientific investigations have shown that many chemicals used in plastics pharmaceuticals pesticides cosmetics food additives etc are endocrine disrupting chemicals EDCs EDCs interfere in various ways with hormones such as estrogens and androgens and can have significant adverse effects on many behavioral and physiological processes ED effec ...

    SBIR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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