Award Data

Project Summary The objective of this Phase I SBIR proposal is to demonstrate the feasibility of a device designed to connect two small vessels together simply and easily and that would replace the hand suturing technique currently used to connect vessels in microsurgery and macrovascular end to end vascular repair surgeries This completely biodegradable vascular coupling device VCD being devel ...

Project summary Key biophysical properties such as drug binding sites and enzyme catalysis arise can be computer modeled using quantum mechanics but limitations in the accuracy of practical quantum methods have held back progress Over the past five years this situation has changed with exciting and ongoing improvements in the accuracy of density functional theory DFT New and better densit ...

Project Summary Enabling routine DNA sequencing has the potential to improve the understanding of biological processes and relationships as well as aid in medicine forensics and environmental investigations However the potential future benefits of sequencing require a reduction in cost and speed and an improvement in instrumentation accessibility relative to presently commercially available t ...

DESCRIPTION provided by applicant The mission of Bioniks is to develop and commercialize accurate low cost movement analysis systems for clinicians ergonomists athletic trainers and other professionals interested in quantifying human movement Our initial focus is on developing computer enhancements for inexpensive D cameras like the Microsoft Kinect These enhancements surpass the accura ...

PROJECT SUMMARY The goal of the current project is to elaborate upon reconstruct and advance to pivotal trial readiness a multimodal closed loop assessment to treatment mobile application for individuals with mood disorders Major Depressive Disorder MDD is a recurrent and disabling condition and a leading cause of global disease burden Nearly half of the patients fail to respond to psycho ...

Summary Statement and Abstract Stem cell technology is revolutionizing regenerative medicine and cell based therapies One of the promising applications of this technology is stem cell derived platelet Platelets are in high demand for a number of medical treatments but general or matching sources may be limited for various reasons A continuous donor independent and universally compatible suppl ...

ABSTRACT PuraCathandapos s goal is to develop an FDA approved catheter hub disinfection system for peripherally inserted central catheter PICC that dramatically reduces catheter related blood stream infections CRBSIs using LED Ultra Violet UV light In Phase I of this SBIR project we propose to optimize the ease of use and robustness to enable home use The current CRBSI infection rate is e ...

DESCRIPTION provided by applicant Genetic studies have been conducted predominantly in cohorts of individuals of European ancestry By there were approximately ten times as many published genome wide association studies GWAS in people of European ancestry than studies in people of all other ancestries combined This research disparity has led to an uneven understanding in the genetic b ...

Abstract In this Commercialization Readiness Pilot CRP Program application we propose to commercialize and bring to market EyeArt a fully automated high throughput retinal image analysis based diabetic retinopathy DR screening tool which has been developed and already validated in bench tests on very large real world data by developing and executing a market access plan conducting a pi ...

The goal of the proposed research is to develop an improved method RealSeq DC to prepare libraries of cell free DNA cfDNA for next generation sequencing NGS cfDNAs which are found in blood and in other bodily fluids represent promising minimally invasive liquid biopsy samples for human cancer and prenatal diagnosis of fetal genetic diseases cfDNAs comprise highly fragmented double str ...