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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

  1. Developmental Neurotox Assay using Scalable Neurons and Astrocytes in High Content Imaging

    SBC: Aruna Biomedical, Inc.            Topic: B

    There is unmet need for rapid, cost effective in vitro methods to identify chemicals that pose a hazard to the human brain. A number of in vitro assays utilizing primary cells have been tested in an effort to devise effective models to prioritize chemicals for further in depth toxicity studies. However, isolation of primary human neural tissue is cost and labor intensive, and cannot be produced in ...

    SBIR Phase II 2014 Environmental Protection Agency
  2. RADIOGRAPHIC CONTRAST TO DIFFERENTIATE CAVITATED FROM NON-CAVITATED DENTAL CARIES

    SBC: FIREFLY HEALTH INNOVATIONS NE, INC.            Topic: NIDCR

    DESCRIPTION provided by applicant This project aims to improve the accuracy of tests for early tooth decay dental caries specifically for interproximal surfaces where the posterior teeth abut one another In these regions there is no physical space to visually inspect or probe for caries Instead dentists rely on bitewing X rays BWs But dentists cannot tell whether lucencies observed ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A study to improve the fit of HIV prevention methods

    SBC: THEYFIT, LLC            Topic: NICHD

    DESCRIPTION provided by applicant A policy statement by the World Health Organization notes that the male latex condom is the single most efficient available technology to reduce the transmission of HIV and other sexually transmitted infections Unfortunately despite decades of condom promotion efforts condoms usage rates remain disappointingly low Between one third and one half of men ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Friends, Family, and Food: Interactive Virtual Environments for Children with Food Allergies

    SBC: VIRTUALLY BETTER INC            Topic: NICHD

    DESCRIPTION provided by applicant Pediatric Food Allergy FA is recognized as a serious public health concern that affects approximately percent of children with symptoms affecting multiple organ systems including skin the respiratory tract and the GI tract Food induced anaphylaxis which is a rapid potentially life threatening reaction can occur in more serious cases Despite the s ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Pegasys VR: Integrating Virtual Humans in the Treatment of Child Social Anxiety

    SBC: VIRTUALLY BETTER INC            Topic: NIMH

    DESCRIPTION provided by applicant Anxiety disorders are the most common psychiatric disorders among youth with lifetime prevalence ranging between of the general population Among anxiety disorders social anxiety disorder SAD affects of all youth resulting in significant short and long term impairment including increased likelihood of substance abuse limited academic achievemen ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Personalized Assistive Technology to Improve Dementia Care at Home

    SBC: SimpleC, LLC            Topic: NIA

    DESCRIPTION provided by applicant This Fast Track SBIR application submitted by SimpleC of Atlanta Georgia requests funds to test our current behavior management technology for persons with dementia PWD the SimpleC Companion and to develop and test a new mobile tablet the SimpleC Wellness Coach in the in home aging in place market where the overwhelming majority of PWD receive their ca ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Bioengineered Recombinant FVIII

    SBC: EXPRESSION THERAPEUTICS LLC            Topic: NHLBI

    DESCRIPTION provided by applicant The manufacturing of recombinant coagulation factor VIII is a complex labor and capital intensive endeavor Of the recombinant proteins currently marketed coagulation factor VIII is manufactured with the lowest efficiency and is by far the most expensive on a per unit mass basis with a pharmacy price of $ per gram The goal of the current applicatio ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Apical Access System with Universal Connector for Beating Heart LVAD Implantation

    SBC: APK ADVANCED MEDICAL TECHNOLOGIES, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant The objective of this proposal is to complete development of a long term universal Apical Access System AAS to improve clinical outcomes and expand the role of left ventricular assist device LVAD therapy The treatment of end stage heart failure HF is the greatest challenge both clinically and economically to the U S health care system today With andg ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Bioengineered factor VIII gene therapy for hemophilia A

    SBC: EXPRESSION THERAPEUTICS LLC            Topic: NHLBI

    DESCRIPTION provided by applicant The overall goal of this proposal is to conduct a gene therapy clinical trial incorporating genetically modified hematopoietic stem cells HSCs for persons with hemophilia A In a series of recent studies we have shown that the transplantation of genetically engineered HSCs can restore factor VIII fVIII activity to curative levels in hemophilia A mice and t ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. A Microneedle Array System for Transcutaneous Nerve Mapping

    SBC: Axion Biosystems, Inc.            Topic: 105

    DESCRIPTION provided by applicant The proposed study combines novel electronics and microfabrication techniques to create a non invasive research platform for targeted stimulation and characterization of human peripheral nerves This Phase II proposal involves two significant developments for high resolution peripheral nerve interfacing Aim will develop high resolution and low noise skin su ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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