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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Novel commensal polysaccharide treats multiple sclerosis through Treg modulation
SBC: SYMBIOTIX BIOTHERAPIES, INC. Topic: NIAIDDESCRIPTION provided by applicant Multiple sclerosis MS is a chronic demyelinating inflammatory disease that is the most common neurological disease of young adults affecting over patients in the US and over million patients worldwide MS is a disease of high unmet medical need currently treatable with one of twelve FDA approved drugs all of which result in either significant i ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Human monoclonal antibodies for prevention of S. aureus infections
SBC: SORRENTO THERAPEUTICS, INC. Topic: NIAIDDESCRIPTION provided by applicant Using mouse monoclonal antibodies mAbs raised against the mediators of quorum sensing QS the Auto Inducing Peptides AIPs researchers at The Scripps Research Institute TSRI have demonstrated that S aureus infections can be prevented in animal challenge models This approach known as quorum quenching QQ is unique in at least two significant ways fi ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
ECG Device for LQTS Screening in Newborns, Phase II
SBC: QT Medical, Inc. Topic: NHLBIDESCRIPTION provided by applicant The congenital long QT syndrome LQTS is thought to occur in in infants and cause of deaths from SIDS sudden infant death syndrome Electrocardiograms ECGs can detect LQTS before fatal cardiac events happen In our Phase I STTR project we successfully developed and tested an ECG device designed for LQTS screening in newborns This device n ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
Mitochondrial Antioxidant Neurodegenerative Therapeutics: XJB-5-131 Derivatives
SBC: SOLANO PHARMACEUTICALS, INC. Topic: NINDSDESCRIPTION (provided by applicant): Oxidative damage to mitochondrial is a major source of toxicity in diseases such as Alzheimer's (AD), Parkinson's (PD), and Huntington's diseases (HD). Mitochondria are energy powerhouses of the cell, and decline in their function by oxidative damage is a common feature among neurodegenerative diseases. Despite years of effort, however, generic ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of PAR2 Inhibitors for the Treatment of Nonalcoholic steatohepatitis
SBC: OASIS PHARMACEUTICALS, LLC Topic: NIDDKDESCRIPTION provided by applicant Non alcoholic steatohepatitis NASH is characterized by fatty changes in the liver with inflammation and hepatocellular injury that in advanced stages leads to fibrosis and cirrhosis and high mortality rates NASH is frequently associated with other common metabolic abnormalities such as insulin resistance and visceral obesity Liver transplantation is curren ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
Nonlinear Computation Tool to Chart Trajectories of Bipolar Disorder
SBC: Biomedical Development Corporation Topic: 103DESCRIPTION provided by applicant Bipolar disorder BD is a complex chronic illness characterized by recurrent often dramatic mood changes Self management of BD is an important component of treatment but is likewise complex and can be fraught with difficulties including misunderstanding of the condition and a lack of self awareness Combined with the nationwide shortage of mental healthcare ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Phase IIB: Portable Device for Telecare Monitoring of Elderly People
SBC: BIOSENSICS LLC Topic: NIADESCRIPTION provided by applicant We propose to further develop field test and commercialize a reliable and robust sensor technology that allows the objective assessment of daily physical activity risk of falling frailty and activity organization among older adults in he home and community This is a Phase IIB STTR application During Phases Iandamp II BioSensics LLC in collaboration wit ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Brain penetrant Hsp90 inhibitors for Alzheimer's disease
SBC: YUMA THERAPEUTICS CORPORAITON Topic: NIADESCRIPTION provided by applicant Neurodegeneration in Alzheimerandapos s disease AD may result from deposition of A as plaques in brain tissue However less effort has been made to elucidate the role of tau containing neurofibrillary tangles NFTs in AD Accumulating evidence suggests that tau containing NFTs is an important component in the initiation and progression of AD and other neu ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
Automated Image-based Biomarker Computation Tools for Diabetic Retinopathy
SBC: EYENUK, INC. Topic: NCATSDESCRIPTION provided by applicant In this STTR project we present EyeMark a set of advanced image analysis tools for automated computation of biomarkers for diabetic retinopathy DR using retinal fundus images Specifically we will develop tools for computation of microaneurysm MA appearance and disappearance rates jointly known as turnover rates for use as a biomarker in quantifying D ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health -
Extending Genome-Phenome Analysis
SBC: SimulConsult, Inc. Topic: 172DESCRIPTION provided by applicant The declining cost of whole exome sequencing WES is nearing the point at which the spread of WES into clinical practice will be limited largely by the cost of interpreting the results and comparing them to the patientandapos s clinical findings This project builds on our demonstrated capability to reduce this interpretation cost by pairing our diagnostic sof ...
STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health