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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Maximizing cancer synthetic lethality using dual PI-3K/PARP inhibitors

    SBC: SignalRx Pharmaceuticals Inc.            Topic: NCI

    PARP inhibitors PARPi are particularly efficacious in tumors deficient in the BRCA tumor suppressor genes but of limited activity in BRCA competent tumors There is an unmet medical need to develop targeted therapeutic agents which will augment PARPi activity for BRCA wild type cancers and to increase chemo radiosensitivity in these malignancies BRCA proteins are essential components ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Target Identification for Novel Small Molecule Therapeutic for Alzheimer's disease

    SBC: CoPlex Therapeutics, LLC            Topic: NIA

    ABSTRACT Traditional approaches to drug development for Alzheimer s disease are becoming increasingly expensive and in many cases disappointingly unsuccessful Based on preliminary in vitro and in vivo studies we have identified a novel small molecule methyl dimethyl oxo dihydrobenzo c naphthyridine carboxylate UK that significantly decreases A production and pro in ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Whole Brain Nanoscale Preservation Imaging

    SBC: Nectome Inc.            Topic: 101

    Abstract Summary Nectome will create technologies to enable whole brain nanoscale preservation and imaging a vital step towards a deep understanding of the mind and of the brainandapos s diseases Current brain processing technologies compromise between whole brain applicability or nanoscale resolution our technologies will achieve both si multaneously Similar to the way that next generation ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Innovative Aerodynamic Modeling for Aeroservoelastic Analysis and Design

    SBC: M4 ENGINEERING, INC.            Topic: T401

    We propose the development of a novel aerodynamic modeling approach making use of fully unstructured grids for unsteady panel aerodynamic models for aeroelastic and aeroservoelastic analysis. The unsteady aerodynamic code will be integrated with an existing suite of aeroelastic and aeroservoelastic analysis tools making it possible to perform aeroelastic and aeroservoelastic analysis of complex v ...

    STTR Phase II 2016 National Aeronautics and Space Administration
  5. Multifunctional Environmental Digital Scanning Electron Microprobe (MEDSEM)

    SBC: CHROMOLOGIC LLC            Topic: T801

    Chromologic (CL) and the California Institute of Technology (Caltech) propose to continue the Phase II STTR development and demonstration of a Multifunctional Environmental Digital Scanning Electron Microprobe (MEDSEM) instrument that transmits high energy beams of electrons sequentially using a two-dimensional array of multiple, miniaturized electron probes into a planetary atmosphere and strike ...

    STTR Phase II 2016 National Aeronautics and Space Administration
  6. High Performance Hybrid Upper Stage for NanoLaunch Vehicles

    SBC: PARABILIS SPACE TECHNOLOGIES INC            Topic: T101

    Parabilis Space Technologies, Inc (Parabilis), in collaboration with Utah State University (USU), proposes further development of a low-cost, high-performance launch vehicle upper stage that uses a high density, storable oxidizer and a polymer fuel grain as propellants in response to solicitation T1.01, Affordable Nano/Micro Launch Propulsion Stages. This effort will build upon the successful opti ...

    STTR Phase II 2016 National Aeronautics and Space Administration
  7. A Coupled System for Predicting SPE Fluxes

    SBC: PREDICTIVE SCIENCE INCORPORATED            Topic: T602

    Solar Particle Events (SPEs) represent a major hazard for extravehicular maneuvers by astronauts in Earth orbit, and for eventual manned interplanetary space travel. They can also harm aircraft avionics, communication and navigation. We propose to develop a system to aid forecasters in the prediction of such events, and in the identification/lengthening of "all clear" time periods when there is ...

    STTR Phase II 2016 National Aeronautics and Space Administration
  8. Advanced Gas Sensing Technology for Space Suits

    SBC: INTELLIGENT OPTICAL SYSTEMS, INC.            Topic: T601

    The gas sensor in the PLSS of the ISS EMU will meet its projected life in 2020, and NASA is planning to replace it. At present, only high TRL devices based on infrared absorption are candidate replacements, because of their proven long-term stability, despite their size and power consumption and failures in the presence of liquid water. No current compact sensor has the tolerance for liquid water ...

    STTR Phase II 2016 National Aeronautics and Space Administration
  9. Improved Forecasting of Solar Particle Events and their Effects on Space Electronics

    SBC: CFD RESEARCH CORPORATION            Topic: T602

    High-energy space radiation from Galactic Cosmic Rays and Solar Particle Events (SPEs) pose significant risks to equipment and astronaut health in NASA missions. Energetic particles from SPEs associated with flares and coronal mass ejections (CMEs) may adversely affect not only beyond-Low-Earth-Orbit missions, but also aircraft avionics, communications, and airline crew/passenger health. It is cru ...

    STTR Phase II 2016 National Aeronautics and Space Administration
  10. Integrated Monitoring AWAReness Environment (IM-AWARE)

    SBC: AMERICAN GNC CORPORATION            Topic: T1301

    American GNC Corporation (AGNC) and Louisiana Tech University (LaTECH) are proposing a significant breakthrough technology, the Integrated Monitoring AWAReness Environment (IM-AWARE) consisting of an Enterprise Infrastructure with closely coupled smart sensor networks and Enhanced IT Security to enable: (i) real time monitoring of the distribution systems health; (ii) supporting maintenance operat ...

    STTR Phase II 2016 National Aeronautics and Space Administration
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