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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Development of CaSR nutrient therapy for childhood diarrhea

    SBC: Medosome Biotec, LLC            Topic: NICHD

    Project Abstract Acute infectious diarrhea is a worldwide problem especially among infants young children and immune compromised patients Sadly million children die each year not because of the infections causing diarrhea but due to the associated dehydration The pro absorptive Oral Rehydration Solution ORS is the only recommended oral therapy for children with acute diarrhea yet it ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  2. SA FasL engineered human islets as a novel product for the treatment of type diabetes

    SBC: FasCure Therapeutics LLC            Topic: NIDDK

    PROJECT SUMMARY Type diabetes T D is a chronic autoimmune disorder that affects of population worldwide Exogenous insulin treatment is the standard of care for T D but often negatively affects the quality of life and is ineffective in preventing recurrent hyperglycemia episodes and chronic complications Recent studies show that human islet allografts can restore long term normoglycemia ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Testing and Commercialization of a Superior Device to Maintain Perioperative Normothermia In Anesthetized Patients

    SBC: Mercury Biomed LLC            Topic: 400

    Project Summary Abstract This proposal presents Phase of the plan of Mercury Biomed LLC for commercializing the new and innovative WarmSmart technology to more effectively keep patients warm during anesthetized surgery The WarmSmart technology is based on IP licensed from the University of Texas at Austin who is the academic partner for this STTR proposal WarmSmart embodies several breakthr ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  4. Personalized dosing of dichloroacetate for the treatment of rare and common diseases

    SBC: Medosome Biotec, LLC            Topic: NICHD

    Pyruvate dehydrogenase complexPDCdeficiencyPDCDis a rare disease of mitochondrial energy failure in which the life of expectancy of affected children is severely truncatedTreatment of PDCD remains a seriousunmetchallengeThere has never been a controlled trial of any intervention for PDCDthusthere is no proven therapy for affected patientsDichloroacetateDCArepresents the first targeted therapy for ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. TheraBracelet: The first and only wearable to instantly improve stroke hand function

    SBC: TheraBracelet, Inc.            Topic: NICHD

    Project SummaryPost stroke hand impairment is highly prevalent and severely restricts functional ability and independenceIn facteveryseconds a new stroke occursand stroke is recognized as the leading cause of long term disabilityYetthere is no assistive device to help hand function at homeevery dayduring activities of daily livingExisting devices such as hand opening orthoses are expensivee gMyomo ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Evolution of an Adaptable Prosthetic Foot Design for Normalization of Biomechanics During Community Participation

    SBC: OHIO WILLOW WOOD COMPANY, THE            Topic: NICHD

    Evolution of an Adaptable Prosthetic Foot Design for Normalization of Biomechanics During Community Participation Summary Abstract The vision of this project is to improve the functional physical mobility of people with lower extremity amputations so that they can more fully and confidently participate in a wider range of activities This will enhance their personal satisfaction thereby improving ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel Probiotic Platform to Treat Necrotizing Enterocolitis

    SBC: MONON BIOVENTURES LLC            Topic: 300

    PROJECT SUMMARY Probiotics hold enormous potential for promoting human health and treating disease One major hurdle to many probiotic products is their lack of persistence in the gut Monon Bioventures MBV and their research partners at the Research Institute at Nationwide Childrenandapos s Hospital RINCH are developing a novel enhanced tunable technology called ProNextTM that allows for a ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Compatibility Between Brain Computer Interface and High Efficiency Augmentative and Alternative Communication Systems

    SBC: Prentke Romich Company            Topic: NIDCD

    Compatibility Between Brain Computer Interface and High Efficiency Augmentative and Alternative Communication Systems ABSTRACT Brain computer interfaces BCI can now enable text production for people who cannot move yet they provide only the simplest communication interfaces and have not been widely adopted Current augmentative and alternative communication AAC systems are widely adopted and ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  9. Commercialization of a Novel Therapeutic for Alzheimer's Disease

    SBC: CoPlex Therapeutics, LLC            Topic: NIA

    ABSTRACT Traditional mon therapeutictarget driven approaches to drug development for Alzheimer s diseaseADare becoming increasingly expensive and in many cases disappointingly unsuccessfulBased on preliminary in vitro and in vivo studies we have identified a novel small moleculemethyldimethyloxodihydrobenzo cnaphthyridinecarboxylateBNCthat significantly decreases neuroinflammation and production o ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Tissue Engineered Intestine

    SBC: NANOFIBER SOLUTIONS, LLC            Topic: 300

    PROJECT ABSTRACT Short bowel syndromeSBSis a major clinical problem affecting newbornschildren and adultsfor which there is currently no known cureThe disorder results from the functional or anatomic loss of extensive segments of small intestine rendering the intestinal absorptive capacity severely compromisedSBS is clinically defined by malabsorptiondiarrheasteatorrheafluid and electrolyte distur ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
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