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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Preclinical Testing of a Novel Flow Diverting Stent for Treating Intracranial Aneurysms
SBC: NeuroSigma, Inc. Topic: 101DESCRIPTIONprovided by applicantThe purpose of this project is to develop an improvedminimally invasive treatment for intracranial aneurysmsIntracranial aneurysms are spherical outpouchings of blood vessels in the head that result from weakness in the vessel wallUnruptured aneurysms are present in approximatelyof the general populationand rupture can be devastating with a high morbidity and mortal ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
A user-friendly scalable microfluidic platform for enhanced neuron-cell culture
SBC: Xona Microfluidics, Inc. Topic: 101DESCRIPTIONprovided by applicantNeuron cell culture is widely used for studies in basic researchdrug discoveryand toxicity testingTraditional neuron cell culture approaches result in random growth of processes which prevent the study of their unique polarized morphologyOur goal is to provide robustuser friendlyand cost effective culture platforms to manipulate and access neurons and their subcellu ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
ARCHER- An Extremely Fast Medical Radiation Dose Computing Software
SBC: VIRTUAL PHANTOMS INC Topic: NIBIBDESCRIPTIONprovided by applicantThe goal of this project is to develop a commercial software package for rapid Monte Carlo based dose computation in imaging and radiation therapyThe product takes advantage of a desktop parallel computer equipped with emerging hardware originally developed gaming and high performance computingThe project is motivated by the fact that the market is ripe for a produc ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Developing novel RPPA for the detection of metastatic prostate cancer
SBC: TYMORA ANALYTICAL OPERATIONS LLC Topic: 102PROJECT SUMMARY Reverse phase protein arrayRPPAhas emerged as a promising antibody based highly quantitative proteomic technology suitable for profiling proteins in hundreds to thousands of patient samplesThe throughputsensitivityand cost effectiveness of RPPAtogether with its ability to deal with minuscule sample amountshave propelled applications of the technology in basicpreclinical and clinica ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Pre Clinical Safety and Efficacy of TRB N for the Treatment of Periodontal Disease
SBC: TRAVERSE BIOSCIENCES, INC. Topic: NIDCRPROJECT SUMMARY ABSTRACT Traverse Biosciences Inc is a pre clinical stage drug development company working to commercialize new chemical entities which act to resolve inflammatory conditions through pleiotropic host modulation of pathologically unrestrained matrix metalloproteinases MMPs and pro inflammatory cytokines The companyandapos s lead drug candidate TRB N is a proprietary chemic ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Development of peptide inhibitors for neuroinflammation and neurodegeneration
SBC: PROVAIDYA Topic: NIADESCRIPTION provided by applicant The prevalence of Alzheimerandapos s disease AD is poised to increase exponentially with the growing aging population worldwide In the United States total annual costs of AD care are projected to increase from $ billion in to over $ trillion in Paucity of disease modifying therapies capable of slowing the disease progression is an acute unmet ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Rapid Immunodiagnosis of Drug-Resistant Bacterial Pathogens
SBC: SILVER LAKE RESEARCH CORPORATION Topic: NIAIDPROJECT SUMMARY ABSTRACT This proposal describes Phase II of the development of a rapid immunoassay test kit for the determination oflactam antibiotic resistanceto be used as a point of care diagnostic test for urinary tract infectionsTodayantibiotics for UTI are prescribed empiricallywith no diagnostics available to clinicians to avoid treating resistant infections with the very drug to which the ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Targeted Epigenetic Therapy for Triple-Negative Breast Cancer
SBC: PARKSIDE SCIENTIFIC INC. Topic: 102DESCRIPTIONprovided by applicantTriple negative breast cancerTNBCis one of the most aggressive forms of human cancerand currently has no targeted therapyChemotherapy is the only available treatment for TNBC patientsbut is deleterious and not effective once tumor spreadsTNBC represents a major unmet medical needaboutof breast cancer incidenceswomen worldwide inare TNBCTNBC disproportionally affects ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Intra procedure Deformable Ultrasound MRI Fusion for Prostate Biopsies
SBC: ZMK Medical Technologies, Inc. Topic: 102This Phase II proposal is a continuation of our successful Phase I grant whose overarching goal is to develop a more robust and accurate method for the deformable fusion of pre operative magnetic resonance images MRI and intra procedure trans rectal ultrasound TRUS images to guide prostate biopsy Prostate cancer is a major cause of death in the U S and biopsy is the gold standard for its dia ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health -
Skin Sympathetic Nerve Activity and Cardiac Arrhythmias
SBC: ARRHYTHMOTECH Topic: NIDADESCRIPTION provided by applicant The objective of this Phase II STTR grant application is to continue the R Randamp D efforts initiated in Phase I The long term objective for Arrhythmotech is to develop and market an instrument for the simultaneous recording of sympathetic nerve activity SNA and electrocardiogram ECG using electrodes on the skin This method neuECG was discovered in Dr ...
STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health