Award Data

CONCUR develops a computational framework for assessing and characterizing urban environments stability or fragility in response to volatility and stress, identifying specific weaknesses as well as key tipping points which could lead to rapid systemic failure. CONCUR explicitly models urban environments as emergent complex systems, focusing attention on the critical triggers that could lead to rap ...

Optical cryocoolers, which are compact and produce no vibrations, are ideal for many electronics and sensor applications. In particular, some advanced metrology systems require cooling to around 124 K, the temperature at which the coefficient of thermal expansion for crystalline silicon goes through a null point. Currently, the dominant solid-state cooling technology is thermoelectric cooling, whi ...

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terriblemorbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditionalvaccines have proven to be a huge contribution to public health, they do have some limitations especially in the cont ...

Flow Pharma, Inc. is a biotechnology company in the San Francisco Bay Area developing fully synthetic cytotoxic T lymphocyte (CTL)stimulating peptide vaccines for Marburg virus. The FlowVax vaccine platform allows us to create dry powder formulations of biodegradablemicrospheres and TLR adjuvants incorporating class I and class II T cell epitopes. FlowVax vaccines can be designed for delivery by i ...

The unique scale, population density, complexity, and connectedness of megacities requires new tools for detecting and assessing risks related to civil unrest, rule of law, terrorism, and other sources of instability, and for understanding the underlying dynamics. In addition, gray zone operations pose a new and strategically important class of threats to the stability of nation states and cities ...

Boston Fusion Corp. and Arizona State University will research and develop REsilience & Stability in DENse Terrains (RESIDENT), a multi-model, multi-scale framework for assessing indicators of stability and resilience in dense urban environments. Our team consists of subject matter experts in the Social and Computer Sciences providing the bedrock on which to build accurate mathematical models of u ...

Volatile organic compounds (VOCs) in air, especially in closed environments pose a major health threat. There is a critical need to remove these pollutant, and biofiltration is a promising solution to this need. This is a Phase II STTR proposal is to develop a novel, modular and scalable approach to biofiltration for effective management of air pollutants in closed environments. We propose a novel ...

We propose to investigate, in collaboration with MGH Voice Center and Altec, Inc., application of surface electromyography (sEMG) to assessing cognitive workload, strain, and overload. Specifically, sEMG sensors placed on the face and neck will detect emotional/motor responses to workload strain. The proposed effort will build on the substantial sEMG experience of our partner, MGH (including resea ...

Vibrant Corporation and Sandia National Laboratories (SNL) propose to apply Process Compensated Resonance Testing (PCRT) to the DLA's need for an NDI method to detect counterfeit, nonconforming and improperly processed materiel. PCRT collects and analyzes the resonance frequencies of a component to detect structural defects, characterize material, analyze population variation, monitor manufacturin ...

The introduction of substandard or counterfeit materials into the DoD supply chain can have extremely expensive, and potentially life threatening, consequences. Current techniques used to detect nonconforming materiel can be destructive (e.g., manual sectioning and inspection of a part), time consuming and expensive (e.g., micro-computed tomography, ultrasound), or provide only limited informatio ...