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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. An Agent-Based Modeling Platform for Environmental Biotechnology

    SBC: MICROVI BIOTECH, INC.            Topic: NIEHS

    DESCRIPTION provided by applicant Hazardous compounds in waters and soils are subject to a complex dynamic web of interactions among physical chemical and biological constituents in the natural environment Computational modeling has been proven indispensable to hazardous substances remediation particularly integrated modeling of pollutant hydrogeological fate and transport For the first t ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Development of An Integrated High Throughput Imaging and Image Analysis Platform for Muscle

    SBC: CytoInformatics LLC            Topic: NIA

    DESCRIPTION provided by applicant There is growing awareness that weakness of muscle is a significant biomedical health issue associated with many different chronic diseases and aging There are a variety of different diseases that affect muscle including muscular dystrophy fibromyalgia cerebral palsy amyotrophic lateral sclerosis and myasthenia gravis each of which carries its own uniqu ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Wearable Neurophysiological Monitoring Device for Circadian Rhythm Assessment and Intervention

    SBC: Cognionics, Inc.            Topic: A16AT014

    This Phase I STTR project will develop a platform to demonstrate high-quality, multi-modal acquisition of neurophysiological signals, including EEG, heart rate/blood oxygenation via photoplethysmography (PPG), electrodermal (EDA) activity, temperature plus environmental factors such as ambient light and sound in a simple, wearable headband. The hardware will be coupled with the development of a cl ...

    STTR Phase I 2016 Department of DefenseArmy
  4. High Gain, High Power PCSS with Integrated Monolithic Optical Trigger

    SBC: NESS ENGINEERING, INC.            Topic: A14AT004

    The objective of this Phase II proposal is to continue the development of a Photoconductive Semiconductor Switch (PCSS) with an integrated optical trigger that can switch at least 30 kV, 1 kA, 20 ns pulses with jitter 108 shots. Ness Engineering, Inc. (NEI) and Texas Tech University (TTU) propose to utilize wide bandgap materials to demonstrate lock-on switching and allow much less optical trigger ...

    STTR Phase II 2016 Department of DefenseArmy
  5. Maximizing cancer synthetic lethality using dual PI-3K/PARP inhibitors

    SBC: SignalRx Pharmaceuticals Inc.            Topic: NCI

    PARP inhibitors PARPi are particularly efficacious in tumors deficient in the BRCA tumor suppressor genes but of limited activity in BRCA competent tumors There is an unmet medical need to develop targeted therapeutic agents which will augment PARPi activity for BRCA wild type cancers and to increase chemo radiosensitivity in these malignancies BRCA proteins are essential components ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Whole Brain Nanoscale Preservation Imaging

    SBC: Nectome Inc.            Topic: 101

    Abstract Summary Nectome will create technologies to enable whole brain nanoscale preservation and imaging a vital step towards a deep understanding of the mind and of the brainandapos s diseases Current brain processing technologies compromise between whole brain applicability or nanoscale resolution our technologies will achieve both si multaneously Similar to the way that next generation ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Parallel Two-Electron Reduced Density Matrix Based Electronic Structure Software for Highly Correlated Molecules and Materials

    SBC: Q-CHEM INC            Topic: A14AT013

    Variational two-electron reduced-density-matrix (v2RDM) methods can provide a reference-independent description of the electronic structure of many-electron systems that naturally captures multireference correlation effects. These methods offer one of the few possible routes to performing the large-active-space computations that are necessary for the qualitative description of strongly-correlated ...

    STTR Phase II 2016 Department of DefenseArmy
  8. Electronically Tunable High-Power Infrared Lasers for Standoff Detection Applications

    SBC: Pranalytica, Inc.            Topic: A14AT015

    In response to the Army STTR Topic A14A-T015 solicitation for tunable high-power LWIR lasers for standoff detection applications, Pranalytica proposed to develop a compact, rugged and highly reliable wavelength tunable quantum cascade laser (QCL) module delivering over 5W of peak power and over 0.5W of average power in the spectral region spanning from 7 to 11m. The proposed approach is based on a ...

    STTR Phase II 2016 Department of DefenseArmy
  9. Development of Alkontrol herbal for Treating Alcohol Abuse

    SBC: NATURAL PHARMACIA INTERNATIONAL, INC.            Topic: NIAAA

    DESCRIPTION provided by applicant This application for a Fast Track STTR award represents a collaboration between Natural Pharmacia International Inc NPI and McLean Hospital to initiate steps toward commercializing a isoflavone botanical product for treating alcoholism Excessive use of alcohol accounts for much of the public health burden related to alcohol use disorders including fetal a ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Technologies to Target Circadian Rhythm Disruption in PTSD

    SBC: BIOSENSICS LLC            Topic: A16AT014

    Circadian rhythm disruption misalignment causes fatigue and a variety of physical and mental ailments, and is a clinical feature of posttraumatic stress disorder (PTSD); it is also closely linked to the severity of PTSD. BioSensics, in collaboration with the Division of Sleep and Circadian Disorders at Brigham and Womens Hospital, will develop a circadian rhythm and sleep coach, Rhythm Sleep, to m ...

    STTR Phase I 2016 Department of DefenseArmy
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