Award Data

This Small Business Technology Transfer (STTR) Phase I project supports the development of a medical device that enables minimally invasive graft-based reconstruction of the urethra as a long-lasting treatment for male urethral stricture, a class of conditions causing restrictions in flow. Approximately 1% of men on Medicare are treated for stricture annually, and an estimated 1 in 5 men will get ...

The broader/commercial impact of this STTR Phase 1 project will develop an automated system that significantly increases the speed, reliability, and accuracy of disease severity assessment in ulcerative colitis (UC) patients. This lifelong debilitating disease impacts almost 1 M US patients, and developing effective treatments requires accurate, reliable, and timely scoring. Currently, the FDA-app ...

The broader/commercial impact of this SBIR Phase I project leverages recent advances in additive manufacturing to solve key technical hurdles and design deficits of current industry standard microcapillary needles. Microinjection is a well-established engineering technique and widely used in research and medical applications such as drug discovery and development, fertility treatments, and genetic ...

The broader/commercial impact of this SBIR Phase I project is to start validating a novel high-intensity focused ultrasound (HIFU) device for minimally invasive treatment of brain tumors. The current standard of care is a highly invasive cranial flap resection, which not only risks infection, uncontrolled bleeding, and damage to healthy tissue, but also has prolonged post-operative recovery. Altho ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project will address concerns about the shortage of materials for Lithium-ion batteries as the number of electric vehicles increases. Lithium Sulfur (Li-S) batteries offer an opportunity because sulfur is more readily available, lower cost, and environmentally friendly. Unlike lead-acid batteries, Li-S batter ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to reduce the morbidity and mortality of patients undergoing surgery. Inadvertent bleeding during surgery represents a critical problem that occurs during all types of procedures on millions of patients around the world. This project will advance a robotic surgical tool system using artific ...

The broader impact/commerical potential of this Small Business Innovation Research (SBIR) Phase I project will be a potentially significant reduction in medication-related falls, injuries, and deaths, as well as a reduction in fall-related medical costs. The number of older adults dying from falls increased by a factor of three between 2000 and 2016, with increased medication use possibly contribu ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to develop a new probe to detect low levels of viral load, such as that causing COVID-19. Rapid and reliable kits are not currently readily available. This project will provide rapid detection of viral material using exsiting cost-effective techniques with fewer detection errors. Being able ...

Current state-of-the-art object detection algorithms are almost exclusively based on Deep Convolutional Neural Network (DCNN). These algorithms all require a large amount of labeled examples for each of the object categories they can recognize. These algorithms will fail for novel objects that only very few or even no prior examples are available. These algorithms are also far less accurate when c ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project will be to develop technology to conserve scarce water resources and improve crop management practices. Agricultural production uses a great deal of water. In California alone, 80% percent of all water usage goes to agriculture. As communities expand and drought conditions develop, the competi ...