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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Target Identification for Novel Small Molecule Therapeutic for Alzheimer's disease
SBC: CoPlex Therapeutics, LLC Topic: NIAABSTRACT Traditional approaches to drug development for Alzheimer s disease are becoming increasingly expensive and in many cases disappointingly unsuccessful Based on preliminary in vitro and in vivo studies we have identified a novel small molecule methyl dimethyl oxo dihydrobenzo c naphthyridine carboxylate UK that significantly decreases A production and pro in ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Multi-Modality Image Data Fusion and Machine Learning Approaches for Personalized Diagnostics and Prognostics of MCI due to AD
SBC: MS Technologies Corporation Topic: NIAAlzheimer s Disease AD is the most common form of dementia and the sixth leading cause of death in the US More than million people in the US currently have AD and the direct health care cost is over $ billion per year Detection of early phase of AD namely Mild Cognitive Impairment MCI can delay prevent and treat this serious disease The project will develop a clinically feasible sy ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Fully Metallic Self-Fragmenting Structural Reactive Materials Using Composites and Alloys Comprised of Aluminum, Lithium, and Magnesium
SBC: Adranos Energetics LLC Topic: DTRA16A002While aluminum casing materials provide some enhanced performance and thermal loading to explosive ordinance, their overall effectiveness is highly limited by incomplete combustion and long residence times. In order to reduce these problems, the casing material must be designed to facilitate rapid fragmentation through either specialized casing geometries or greatly refined initial particle sizes. ...
STTR Phase I 2016 Department of DefenseDefense Threat Reduction Agency -
Immuno-CometChip for Human Skin Basal Cell Genotoxicity Testing
SBC: TREVIGEN, INC. Topic: 113DESCRIPTION provided by applicant The objective of this Phase STTR research is to quantify genotoxicity in basal cell keratinocytes from organotypic cultures Epiderm in response to commonly used chemical agents The proposed product is a Comet Chip assay that measures DNA damage in basal cells derived from a reconstructed human epidermis Technical questions that will be addressed are Ca ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
DOEYK: Detecting Objects with Enhanced YOLOv3 and Knowledge Graph
SBC: Intelligent Automation, Inc. Topic: DTRA19B002Current state-of-the-art object detection algorithms are almost exclusively based on Deep Convolutional Neural Network (DCNN). These algorithms all require a large amount of labeled examples for each of the object categories they can recognize. These algorithms will fail for novel objects that only very few or even no prior examples are available. These algorithms are also far less accurate when c ...
STTR Phase I 2020 Department of DefenseDefense Threat Reduction Agency -
Developing a novel drug for neurobehavioral deficits in FASD
SBC: COGTHERA LLC Topic: 230Project Summary Fetal Alcohol Spectrum Disorder (FASD) is a debilitating condition causing a wide range of disabilities including behavioral and intellectual deficits, facial dysmorphology, and organ malformations. This disorder has a profound impact on health care burden and cost; as many as 5% of children within the United States are affected by this condition, with lifetime treatment costs reac ...
STTR Phase I 2021 Department of Health and Human ServicesNational Institutes of Health -
General Purpose Radiation Detector Front End and Digital Processor
SBC: H3D INC Topic: DTRA20B002This project aims to create a general-purpose readout architecture that will allow the rapid deployment of next generation detection systems. The system will be based on the development of a programmable general-purpose integrated circuit (GPIC) that has the front-end electronics required to read out signals from a variety of radiation detectors, especially next generation scintillators and semico ...
STTR Phase I 2021 Department of DefenseDefense Threat Reduction Agency -
Automated Point-of-Care Identification of Innocent Still's Murmur in Children
SBC: AUSCULTECH DX LLC Topic: NHLBIPROJECT SUMMARY The overall goal of the proposed research and technology transfer effort is to develop a low cost point of care mobile device based technology for automated identification of Stillandapos s murmur the most common innocent benign and harmless heart murmur of childhood This novel technology could reduce the current rate of over a million children unnecessarily referred to pedia ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Computerizing NIAAA's Best Practices for Youth Screening and Brief Intervention
SBC: COG ANALYTICS, LLC Topic: 400DESCRIPTION provided by applicant The early onset of alcohol misuse during adolescence is a widespread problem in the U S Studies have consistently documented both the short and long term adverse neurophysiological impacts and health risk behaviors associated with alcohol misuse during adolescence Given the magnitude of this problem and its myriad consequences preventing early initiation of ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health -
Novel therapies for inherited muscle diseases
SBC: Medosome Biotec, LLC Topic: NIAMSDESCRIPTION provided by applicant The pursuit of novel therapies informed by the astounding advances in biomedical science of the past half century has been fruitful for many disorders However inherited muscle diseases such as muscular dystrophy remain stubbornly resistant to sophisticated molecular approaches to therapy A few therapies are finally edging towards approval but it has become ...
STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health