Award Data

Orbit Logic and the Fraunhofer USA Center for Experimental Software Engineering propose development of a solution called SCRAMBL (Space Communication Reconstruction and Mapping with Blockchain Ledgering), which will leverage blockchain technology to store and distribute a ledger containing satellite constellation-relevant shared data to enable satellite onboard autonomy cooperative attendance of i ...

Vistexrsquo;s patented Pressure Focusing Layer (PFLtrade;) technology utilizes a computationally optimized mold set that provides the same uniform pressure and temperature as an autoclave. NASA calls for an innovative out-of-autoclave processing method for thin-gauge structures. Vistexrsquo;s PFL process directly addresses this need. Specifically, the PFL processrsquo; core strength is its ability ...

NASA is spearheading the efforts on Urban Air Mobility (UAM) and providing impetus to the industry to follow with concepts for the same. Several manufacturers, as well as, NASA, have come up with concepts for UAM aircraft; mostly using Distributed Electric Propulsion (DEP). However, the multidisciplinary interactions involved and the ability to utilize the distributed propulsors for improved contr ...

Orbit Logic is teamed with the University of Colorado at Boulder to develop Intelligent Navigation, Planning, and Autonomy for Swarm Systems (IN-PASS). The proposed technology builds on proven software ndash; to enable flexible composition of collaborative mission concepts assessed in an open simulation environment. The focus of IN-PASS is rover autonomous navigation ndash; specifically developmen ...

ABSTRACT Advances in molecular biology and genetic engineering have led to the design and use of modified T cells recognize tumors to achieve significant tumor control upon adoptive cell transfer (ACT) to patients. These T cells are either transduced with tumor antigen reactive T cell receptors (TCR), or chimeric antigen receptors (CARs). Recently, a surge in studies with neo-antigen reactive T ce ...

PROJECT SUMMARY According to the CDC, 550,000 Healthcare Associated Infections (HAIs) occur per year in the US, costing ~$100 billion and killing tens of thousands of patients. Reducing HAIs is a top priority of the US DHHS and NIH and experts have called for novel strategies including vaccination to achieve this goal.ExBaq was founded by scientists and business colleagues who have spent years stu ...

Abstract Influenza is the cause of considerable morbidity and mortality globally. Certain groups, i.e., infants, pregnant young women, and older adults are especially at risk for severe disease. Despite immunization being the most effective and economical prophylactic approach, vaccines often provide less than optimal defense against an influenza illness, with efficacies ranging from 10-60%. This ...

Project SummaryThe goal of this project is to further develop an existing smart stethoscope in order to be capable of monitoring pediatric patients at home who suffer from asthma as well as adults with COPD. Lung diseases impose a serious burden on healthcare systems, individuals and governments. The World Health Organization (WHO) found that chronic obstructive pulmonary disease (COPD) and lower ...

The incidence of type 1 diabetes (T1D) has been increasing in the US for reasons that remain elusive. The Centers for Disease Control and Prevention (CDC) reports that T1D is the third most prevalent chronic disease of childhood in the USA, behind asthma and obesity. Approximately 5% of the 30.3 million adults with diabetes in the USA have T1D. The pathogenesis of T1D encompasses a spectrum that r ...

PROJECT SUMMARYRNA is a validated target for drug design, both as therapeutic and as a target. Targeting specific RNA, such as rRNA which are involved in proliferation and survival of bacteria is a promising approach. We are developing fast and low cost methods to screen sequence-specific small molecules for novel anti-ribosomal activities. We will construct sequence-specific chemically modified r ...