Award Data

This SBIR Phase I project proposes to create an innovative educational game that engages secondary school students in learning about the science of anaerobic digestion and the business of biogas production. The Simulated Anaerobic Digester Learning Tool is a casual, simulation-based game that teaches students about the physicochemical operation of an anaerobic digester, as well as an entrepreneuri ...

This Small Business Technology Transfer Phase I project will explore the applicability of a Gabor-domain optical coherence microscopy (GD-OCM) instrument to qualify materials during manufacturing processes. State-of-the-art interferometric instruments yield excellent resolution in depth, discriminating between different layers within a volume; optical microscopy offers high lateral resolution, but ...

The broader impacts/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is in the development of energy-saving window products that are aesthetically pleasing. Aerogel window products have the potential to be transformative to the fenestration industry, due both to the high translucency and low thermal conductivity of the aerogel materials and the particular adva ...

The broader impact/commercial potential of this project includes applications ranging from peak load shifting, grid buffering for renewable energy input, frequency regulation, and chemical conversions. As the percentage of energy from renewables on the grid increases, energy storage will be essential to stabilize the supply and demand. Currently, 20-40% of wind energy is often stranded due to the ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is found in the proposed technology development that facilitates direct, ubiquitous acquisition of key biomedical data, with little or no human intervention or introduction of errors, has the potential to reduce the costs of healthcare and to revolutionize healthcare delivery throughout our so ...

The broader impact/commercial potential of this project is the development of a continuous and low-cost spray-pyrolysis process for making mixed metal oxide (MMO) materials that can be used in the petroleum and chemicals synthesis, precursors for solar panels, electrode materials, fuel cells, oxygen selective membranes, and chemical sensors. Of particular interest are crystalline pyrochlore mixed ...

The broader impact/commercial potential of this project is determined by new consumer products and new industries which would flourish on portable and reliable atomic clocks, gyroscopes, and magnetometers when they become available. Proposed compact thermal and magnetic enclosure reduces the most bulky part of such devices and provides an avenue for further miniaturization. A chip-scale atomic clo ...

Project Summary Human respiratory syncytial virus (RSV) is recognized as the single most important viral cause of acute respiratory disease in infants and young children worldwide. Elderly populations and immunocompromised individuals are also at significant risk for serious RSV disease. Despite this very substantial disease burden imposed by RSV worldwide, there are no vaccines available. Severa ...

Problem to be Solved: Triple-negative breast cancer (TNBC) is a deadly disease that accounts for 15-20% of all diagnosed breast cancers worldwide. Metastatic relapse of TNBC carries a poorer prognosis and lower survival rate compared to other breast cancersubtypes. Therefore, identifying novel targets and new therapeutics to treat patients diagnosed with TNBC remains a significant priority of the ...

DESCRIPTION (provided by applicant): Due to the absence of effective therapies, pancreatic cancer is the fourth leading cause of cancer deaths in both men and women. This study focuses on the development of new small molecule inhibitors targeting Focal Adhesion Kinase against pancreatic cancer. Focal Adhesion Kinase (FAK) has been shown to play an important role in tumor cell survival, including p ...