Award Data

Physical Sciences Inc. and Colorado State University will develop an innovative sensor that enables low-cost infrared hyperspectral imaging though the use of novel sampling algorithms which provide real-world chemical plume detection capability with compressed data and a hardware configuration which enables high frame rate capture of full 2D spatial and 1D spectral data. Compressive sensing techn ...

SI2 Technologies, Inc. (SI2) proposes to develop printed, high-performance ultracapacitors to meet the Army"s need for lightweight energy storage. SI2 will leverage its demonstrated expertise in ink jet printing and our partner"s expertise with carbon nanoparticle synthesis to develop low-cost, flexible, printed ultracapacitors. SI2 has considerable experience in the roll-to-roll deposition of ...

Q-Peak, Inc. in collaboration with CREOL proposes to develop a novel concept of long-wave IR (LWIR) femtosecond laser system. Current laser systems suffer from complexity due to the use of multiple nonlinear stages to achieve the desired wavelength and have issues with power scaling. The proposed system will consist of 2.5 um femtosecond regenerative amplifier system pumping a single OPA stage bas ...

Antimicrobial treatment of military textile systems is intended to provide enhanced protection to the Warfighter in the field by preventing colonization of harmful bacteria that cause problems such as odor, dermatitis, and skin irritation. Current treatments can impart antimicrobial functionality to textiles; however, they all possess broad-spectrum antimicrobial activity, affecting all skin bacte ...

To achieve the goals of this program improving spectral coverage and output power of monolithic QCL sources as well as the development of a production and manufacturing plan - we propose to develop in collaboration with MIT Lincoln Laboratory a broadly tunable high power source that is based on Eos"proprietary QCL array technology. The current generation of Eos"commercially available fully packag ...

Autonomous or teleoperated navigation of unmanned ground vehicles (UGVs) is difficult even in benign environments due to challenges associated with perception, decision making, and human-machine interaction, among others. In environments with rough, sloped, slippery, and/or deformable terrain, the difficulty of the navigation problem increases dramatically. In this effort, Quantum Signal, LLC, Un ...

DESCRIPTION (provided by applicant): The broad and long-term objective of this project is to amplify the effectiveness of vaccines without the use of chemical or biological adjuvants. We will address this objective by demonstrating the feasibility for small laser- based devices to enhance responses to intradermal vaccination. A number of investigators have shown that a promising new way to make va ...

DESCRIPTION (provided by applicant): We invented an innovative protein induced Pluripotent Stem Cells (piPSCs) technology that generates piPSCs from normal fibroblast and cancer cells within 1-week with 90 4% conversion efficiency. Such high conversion efficiency enables us to pioneer an in situ cell reprogramming technology within the cancers of cancer-bearing animals. Instead of generating iPSCs ...

Project Abstract Active surveillance (AS) is becoming more accepted as a reasonable treatment option for men with low-risk prostate cancer (i.e. Gleason score 6, clinical stage T2a, PSA lt 10). Many AS protocols at major institutions call for a prostate saturation biopsy after initial diagnosis to confirm that the patient has no areas of higher-risk prostate cancer. For most patients who underwent ...

DESCRIPTION (provided by applicant): Cisplatin is a cornerstone therapy for a number of cancers including testicular, bladder, ovarian and lung. It is also used to treat cancers in children. In all cases there is a high incidence of acute kidney injury (AKI) that can also lead to later stage kidney damage. This risk limits its use. We have found in pilot studies that renalase, or peptide fragment ...