Award Data

The broader impact and commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to empower providers with the unprecedented ability to treat patients with chronic inflammatory skin disease effectively and at a lower cost. Today, primary care physicians often refer patients with these conditions to dermatologists for the initial diagnosis and multiple follow-up appo ...

The broader impact/commercial potential of this Small Business Technology Transfer Phase I project are its two intended contributions: it will advance computer vision for navigation and it will create unprecedented opportunity and independence for individuals with visual impairment. 253 million people with blindness or visual impairment around the world experience difficulty to independently navig ...

This STTR Phase I project will develop a transformative platform for inexpensive screening for pancreatic cancer detection, based on profiling of cancer-related proteins from a small blood draw. Pancreatic cancer is one of the deadliest types of cancer, killing over 50,000 each year in the US, and with a five-year survival rate below 7%. However, currently there are no reliable diagnostic tests fo ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) project will be a low-cost, high-performance nanofiltration membrane technology for removing oils, pollutants, and organic materials from highly contaminated wastewater. Industrial activity in the U.S. produces more than 25 billion gallons of wastewater every day, much of contaminated with oils, greases, solv ...

The broader impact of this Small Business Innovation Research (SBIR) project is to drive down healthcare costs by enabling access to data through blockchain technology. The healthcare system is plagued by inefficiencies, many of which boil down to the inability to access the right data at the right time because of technological and business barriers. Leveraging blockchain for data access can drive ...

PROJECT SUMMARY ABSTRACT In response to PAthis Phase I STTR proposal will aim at developing pharmacotherapies that can act aslife savermedications to counteract the neurotoxic effects of synthetic cannabinoidsSCsTowards this goalwe will synthesize CB R antagonists with fast onsets of action that can be administered in an emergency roomERsituationThe rationale is based on the successful soft agonis ...

PROJECT SUMMARY Cognitive decline and deterioration of long term cognitive performance are major side effects of CNS cancer treatmentBrain metastases are the most common CNS malignancies and a common cause of morbidity and mortality in aboutof all cancer patients with systemic diseaseaffecting overpatients in the US annuallyAs most systemic chemotherapy agents do not cross the blood brain barriert ...

PROJECT SUMMARY Cholera is an acute and severe disease caused by the bacterium Vibrio cholerae that is spread primarily through contaminated water sources due to a lack of adequate sanitation infrastructure. The World Health Organization estimates that there are at least 3 million cases globally per year, 40 percent of which are spread through household transmission. Current prevention methods req ...

RESEARCH andampRELATEDUnitPROJECT SUMMARY ABSTRACT In response to PAthe aim of this Phase I STTR proposal is to optimize and develop peripherally actingcannabinoidreceptorCB Rneutral antagonists displaying favorable therapeutic profiles for treating diabetic nephropathyDNDN is a chronic diabetic kidney disease and affectstypeand typediabetic patientsIt is characterized by persistent albuminuria an ...

Development of a Novel Bio Adhesive Mesh System for Abdominal Hernia Repair Project Summary Abstract This project proposes the development of a novel mesh adhesive system for abdominal hernia repair utilizing surface modification of polymer surgical mesh to allow for improved tissue fixation with a poloxamine hydrogel adhesiveMore thanmillion Americans undergo hernia repair with surgical mesh each ...