Award Data

The broader impact/commercial potential of this project is the development of an innovative cyber security solution based on Power Fingerprinting (PFP) for vulnerable wireless networking equipment and smart grid infrastructure. PFP can prevent well-funded adversaries from compromising these critical systems and operate without being discovered. The PFP monitor can assess the integrity directly on ...

This Small Business Technology Transfer (STTR) Phase I project proposes to develop a new low-cost platform for the production of methyl ethyl ketone directly from pretreated cellulosic biomass in a single step using a novel recombinant cellulolytic Bacillus subtilis strain. Methyl ethyl ketone (MEK), also referred to as 2-butanone, is the second most important commercial ketone after acetone. MEK ...

This Small Business Innovation Research (SBIR) Phase I project focuses on the development of a minimally invasive endoscopic surgical device for the treatment of pancreatic cancer. Alarmingly, more than 38,000 Americans will die this year from pancreatic cancer and the average survival time following diagnosis will typically be 6-9 months; a statistic that has not changed significantly over the la ...

This Small Business Technology Transfer (STTR) Phase I project proposes to develop new tools that will make it possible to better predict crop yields under changing climatic and environmental conditions, associate phenotypic expression of desired plant traits with genetic markers, and enable plant breeders to accelerate the development of new crops and varieties under changing climatic conditions. ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to provide a new tool revealing important information regarding skeletal muscle strength and health. Muscle weakness is a pervasive problem across our society, including people with joint disease, aging people, obese people, and people with neuromuscular disorders. All these problems affect ...

DESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...

? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...

DESCRIPTION (provided by applicant): This Phase I application aims at developing a generalizable electrochemical biosensing platform for detection of metal ions in water. Specifically, the main objective of the project is to validate the design of a convenient, cost-effective electrochemical ion (E-ION) sensing platform for direct detection of metal ion contaminants such as mercury (Hg2+), silver ...

DESCRIPTION (provided by applicant): Obstructive sleep apnea (OSA) is the most common type of sleep apnea. OSA affects an estimated 18-40 million adults and 0.7-3% of all children in the US. OSA results in tiredness, depression and fatigue, and has severalassociated common comorbidities. It is believed that over 80% of OSA remains undiagnosed. Poorer and disadvantaged communities are at higher ris ...

DESCRIPTION (provided by applicant): The US Centers for Disease Control and Prevention estimate that 1.6 - 3.8 million concussions occur annually. Although striking, these figures are vast underestimates of the actual number of afflicted individuals because many who have suffered a concussion are never diagnosed because they do not seek medical advice. During competition and practice, athletes are ...