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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Nonlinear Computation Tool to Chart Trajectories of Bipolar Disorder

    SBC: Biomedical Development Corporation            Topic: 103

    DESCRIPTION provided by applicant Bipolar disorder BD is a complex chronic illness characterized by recurrent often dramatic mood changes Self management of BD is an important component of treatment but is likewise complex and can be fraught with difficulties including misunderstanding of the condition and a lack of self awareness Combined with the nationwide shortage of mental healthcare ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Lentiviral Vector for the treatment of Fanconi Anemia

    SBC: Rimedion, Inc.            Topic: NHLBI

    DESCRIPTIONprovided by applicantIn this Phase II STTR application Rimedion seeks to commercialize a novel treatment for patients suffering from Fanconi anemia and request funding for a Phase I II clinical trialThe product will utilize a HIVbased lentiviral vector expressin the Fanconi anemia A proteinThe strong scientific support for this approached is strengthened by a successful Phase I STTRThe ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  3. Recyclable Magnetic Co C Hybrid ROMP Reagents Scavengers and Ligands

    SBC: MATERIA, INC.            Topic: 300

    DESCRIPTION provided by applicant This Fast Track Small Business Technology Transfer study between Materia Inc in Pasadena CA and the University of Kansas intends to build upon successes of our current Phase II Fast Track STTR grant R GM which ends on March Preliminary results serve as a solid foundation for this Fast Track submission entitled andquot Development of Re ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  4. Infant Screening of Early Communication Risk: The CISS, Phase II

    SBC: PAUL H BROOKES PUBLISHING CO., INC.            Topic: Y

    DESCRIPTIONprovided by applicantEffective early intervention depends on reliable screening of risk for communication impairments as soon as possibleEstablished infant communication risk factors include poor attentiongesturessocial connectednessexploratory playand speechAlthough these risk factors can be detected bymosand reliably predict later language and social disordersattempts to detect simila ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Protein Sequencing Tools for Biological Therapeutics

    SBC: PROTEIN METRICS INC            Topic: 400

    DESCRIPTION provided by applicant Mass spectrometry has become a method of choice for identifying and characterizing small quantities of proteins in complex mixtures However the ability to perform the identification in a high throughput fashion has depended on the availability of high quality protein sequence databases This means that proteins from organisms with unsequenced or poorly sequen ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  6. Enhanced multiphoton microscopy through spatial light modulation

    SBC: BOULDER NONLINEAR SYSTEMS, INC.            Topic: 102

    DESCRIPTION provided by applicant Nonlinear optical microscopy techniques and particularly multiphoton fluorescence microscopy have become popular tools for visualizing the three dimensional cellular architecture residing hundreds of microns and up to one millimeter deep in living organisms This is particularly valuable in neurobiology where multiphoton techniques have become widely used fo ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  7. AFM based nanoscale IR Spectroscopy (AFM-IR) as a characterization platform for P

    SBC: Anasys Instruments Corp.            Topic: 300

    DESCRIPTION provided by applicant Anasys Instruments and Prof Lynne Taylor of Purdue propose to develop nanoscale chemical characterization capabilities for drug formulation research This project will build on successful Phase I research demonstrating feasibility of atomic force microscope based infrared spectroscopy AFM IR in pharmaceutical applications This Phase II research will advance ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  8. Investigation of a nanoparticle albumin-bound mTOR inhibitor, nab-rapamycin for t

    SBC: AADI, LLC            Topic: 102

    DESCRIPTION provided by applicant In it is estimated that there will be new bladder cancer cases in the United States resulting in deaths Most cases present with nonmuscle invasive bladder cancer NMIBC Intravesical bacillus Calmette Guerin BCG which elicits a nonspecific local immune response is considered the standard first line treatment However ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. A Percutaneous Ultrasound-Guided Catheter for Organ and Vascular Access

    SBC: PERCEPTIVE NAVIGATION LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Safe and reliable access to major blood vessels and internal organs will be beneficial to patients with cardiovascular disease and cancer An interventional catheter with forward viewing ultrasound imaging capability will be developed to enable image guided access to blood vessels and internal organs Phase experiments demonstrate feasibility of building a hi ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  10. Optimizing HaploSeq for whole-genome phased haplotypes in biomedical applications

    SBC: ARIMA GENOMICS, INC.            Topic: 172

    DESCRIPTION provided by applicant Phenomenal advances in DNA sequencing technologies have enabled systematic identification of genetic variants in human individuals and the recent FDA marketing authorization of the first next generation genome sequencer signals the arrival of a new era of pharmacogenomics and personalized medicine Nevertheless DNA sequencing alone fails to provide complete i ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
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