Award Data

There are currently no vaccines or therapeutics available for Marburg Virus Disease (MVD). Given the specter of weaponization and the terrible morbidity and high mortality rate of MVD, this represents a critical threat to the operational readiness of the Warfighter. While traditional vaccines have contributed greatly to public health, they have some limitations especially in the context of operati ...

Video Demonstration of the Phase I Prototype: http://youtu.be/AIGigEXn12Q Purpose: This project team will develop and test Zaption, a mobile and desktop platform designed to support educators in effectively and efficiently utilizing video (e.g., from YouTube, Vimeo, or their own desktop) as an interactive teaching and learning object. Personalized learning devices (e.g., smartphones, tablets) pop ...

This project will fully develop LabAR, an augmented reality (AR) app for students to perform hands-on physical science investigations. Using the on-device camera, LabAR will augment the environment around the user with simulated instruments and equipment, real-time data visualizations, and annotations. The simulation will be designed to look and feel realistic to maximize transferability of knowle ...

Verdant will be an immersive virtual reality (VR) experience for high school biology students focusing on Mendel's investigation into the heredity of pea plants and the basis of genetics. In Verdant, students revisit Mendel's scientific process by designing and running open-ended crossbreeding experiments at the macroscopic and microscopic levels and recording results, as Mendel did, but in hours ...

Video Demonstration of the Phase I Prototype: http://youtu.be/P74Z5oNAo4c Purpose: This project will develop and test Kiko's Thinking Time, a series of game apps designed to strengthen children's cognitive skills related to executive functioning and reasoning. A principle objective of preschool is to prepare children for later success in school. Most programs focus on activities to support childr ...

Video Demonstration of the Phase I Prototype: http://youtu.be/0FtoN0AX6PE Purpose: This project team will develop and test an app, Speak Agent AAC, intended to increase communication rates and provide individualized supports to students with speech disabilities who use assistive technology to communicate. Among school-aged children with speech communication disabilities, students with Autism Spec ...

Through this STTR contract, we propose to evaluate the efficacy of our vaccine, FlowVax Marburg, in nonhuman primates (NHPs). This will be achieved through four Tasks. In Task 1, we will manufacture the vaccine in a quantity sufficient for the animal studies. In Task 2, we will perform MHC genotyping on a representative population of NHPs and, based on results, select a set of MHC-matched NHPs for ...

The Phase II strategy proposed provides for the development and optimization of a feasible, rapidly scalable, single-use manufacturing platform for the production of a mAb directed against Marburgvirus. Application of BioFactura’s StableFast patented manufacturing platform will result in an economically-produced mAb therapeutic with consistent, targeted properties for safety and efficacy. Charac ...

There is a tremendous need for an all-purpose paint stripper that is safe to handle and that does not harm the environment. The most popular all-purpose paint strippers are based on methylene chloride (MeCl), which is dangerous to workers and harmful to the environment. In particular, it is highly volatile, and if it is used in an area with poor ventilation it is an immediate health hazard. In ext ...

Due to increasing concerns over the long-term health effects of PFOS and PFAS on the human body, regulatory agencies have set limits for the concentrations ofPFOS and PFAS in drinking water.Currently, lab-based PFOA and PFOS water tests cost $200-$300 per sample, with a turnaround time of 2-3 weeks.In the program, 2W iTech LLC Proposes to develop a low-cost fieldable sensing technology for detecti ...