Award Data

This SBIR Phase II proposal provides a sustainable solution for two major environmental challenges in the agriculture and building industry. In the agriculture industry, swine manure treatment is a major problem, both environmentally and economically. Currently, more than 120 million hogs being produced in the US per year, generating more than 6 billion gallons of swine manure that must be treated ...

Industrial Microbes is developing a green fermentation platform to replace carbon-emitting petrochemical production with newer methods that build chemicals out of methane and carbon dioxide.Chemical production is a major source of carbon pollution, responsible for 18% of direct industrialemissions. Our innovation is an engineered microbe that can consume carbon dioxide and methane and produce a ch ...

On-demand cell and tissue samples are critical for both mass trauma care and advanced personalized medical procedures and continue to grow in importance. Biological tissue banks to support these on-demand applications lack safe and effective long-term storage methods. Current cryopreservation techniques and protocols use toxic cryoprotective agents that prevent successful full viability recovery o ...

Ocular injuries have constituted approximately 13% of all casualties from Operation Enduring Freedom/Iraqi Freedom. Of 76 patients that sustained open globe injuries and underwent surgery at Walter Reed National Military Medical Center to restore vision, 38% ultimately went blind.In many cases, severely scarred corneas preclude adequately visualizing the retina and other intraocular structures to ...

The focus of this effort is to enable the deployment of patient-centric and context-aware networked medical systems. Securing medical device communications is a foundational requirement before the Medical Internet of Things can become a reality. Devices and applications need to be provisioned with certified credentials; they need to discover each other through a secure discovery process; and mecha ...

During combat a soldier may incur treatable injuries beyond the expertise of the combat medic. Addressing this by deploying more knowledgeable Medical Officers per-squad could be life-saving and significantly improve battlefield injury recovery. However, limited resources often prevent deployment of such expertise per-squad. During our Phase I RACC development, Neya Systems has successfully demons ...

VecTOR Test Systems, Inc. will develop assay for rapid detection of the Lyme disease pathogen Borrelia burgdorferi in ticks in a field setting. In Phase I prototype assays to detect Borrelia burgdorferi were developed that met Phase I objectives. The development work will continue in Phase II in which the assay with the required sensitivity and specificity will be completed and evaluated in the la ...

Lyme disease is the most common tick-borne disease in North America and one of the fast-growing infectious diseases in the United States.An inexpensive, portable and accurate diagnostic device for the detection of Borrelia bacteria in the deer tick will be developed.The diagnostic device will consist of an efficient extractor for disrupting the hard exoskeleton on the tick, an ultra-sensitive late ...

This proposal is for a subsequent Phase II for the SBIR project Apps for Rapid Epidemiological Surveillance (AREA).Our Phase II accomplishments focused on AREA handheld apps and their use for managing epidemiological data acquisition.Our proposed subsequent Phase II effort will increase the AREA capabilities for data stream integration and decision support by extending the system to a Disease Outb ...

Based on encouraging Phase I feasibility results, we propose developing a novel gene therapy approach to promote guided vascular regeneration in treating extremities after traumatic injury. Our approach is to provide thread-like implants comprised of aligned nanofibrillar collagen scaffolds loaded with Hepatocyte Growth Factor (HGF) vectors (e.g., HGF DNA plasmid, modified mRNA) designed to enhanc ...